{"id":"W3197049258","doi":"10.1182/bloodadvances.2020003534","title":"Targeting pediatric leukemia-propagating cells with anti-CD200 antibody therapy","year":2021,"lang":"en","type":"article","venue":"Blood Advances","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trillium Therapeutics (Canada)","funders":"University of Oxford; University of Bristol; National Institute for Health and Care Research","keywords":"CD19; Minimal residual disease; CD34; Medicine; Leukemia; Immunology; Cancer research; Transplantation; Stem cell; Antigen; Oncology; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005137245,0.0002063141,0.0001903275,0.0001531065,0.00006834637,0.0002286668,0.0001387472,0.000174247,0.0005583296],"category_scores_gemma":[0.00003510062,0.00005363159,0.0001044107,0.0001175575,0.00005661739,0.00008985954,0.0001288538,0.0003272949,0.0002100893],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001737438,"about_ca_system_score_gemma":0.0001087763,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002519709,"about_ca_topic_score_gemma":0.0005871049,"domain_scores_codex":[0.9999651,0.000004438677,0.000002283485,0.000006381427,0.0000124505,0.000009424897],"domain_scores_gemma":[0.999985,0.000002429457,0.000004887162,0.000001644666,0.000001702422,0.000004341143],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000843972,0.00008349521,0.0004906289,0.00005139705,0.000007309282,0.00005214095,0.00001365534,0.0002829588,0.9828839,0.0001597777,0.000172354,0.01571805],"study_design_scores_gemma":[0.00006321965,0.001224643,0.006135376,0.00001066765,0.00005467788,0.0007185836,0.00002348809,0.002710622,0.9739629,0.0000896367,0.01500152,0.000004643818],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901602,0.00350044,0.00441652,0.00008861265,0.00001908247,0.00006705119,0.0001781503,0.0001719194,0.001397986],"genre_scores_gemma":[0.9899356,0.003229589,0.004591872,0.0000876367,0.00001334784,0.00006776277,0.0005032871,0.00001440094,0.001556584],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005583296,"threshold_uncertainty_score":0.001867771,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01476344073809838,"score_gpt":0.3032942440092108,"score_spread":0.2885308032711124,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}