{"id":"W3197139576","doi":"10.1016/j.brs.2021.08.021","title":"Neuromodulatory treatments for psychiatric disease: A comprehensive survey of the clinical trial landscape","year":2021,"lang":"en","type":"article","venue":"Brain stimulation","topic":"Neurological disorders and treatments","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; Centre for Addiction and Mental Health; Health Sciences Centre; Toronto Rehabilitation Institute; Sunnybrook Health Science Centre; Krembil Foundation; University of Toronto; University Health Network","funders":"Department of Psychiatry, University of Toronto; Defense Advanced Research Projects Agency; Servier; University of Toronto; Otsuka America; BrainsWay; Boston Scientific Corporation; Canadian Institutes of Health Research; Sunovion; Centre for Addiction and Mental Health Foundation; Abbott Laboratories; Fondation Brain Canada; Association for Frontotemporal Degeneration; Ministry of Health -Singapore; Beth Israel Deaconess Medical Center; Pfizer; Alzheimer's Drug Discovery Foundation; National Institutes of Health; Medtronic","keywords":"Neuromodulation; Clinical trial; Medicine; Psychiatry; Electroconvulsive therapy; Major depressive disorder; Modalities; Schizophrenia (object-oriented programming); Blinding; Deep brain stimulation; Psychological intervention; Randomized controlled trial; Disease; Internal medicine; Mood; Parkinson's disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaepi_broad"],"consensus_categories":[],"category_scores_codex":[0.07378297,0.0007324402,0.004971403,0.0141737,0.0007119044,0.005631306,0.002128248,0.002895849,0.004240721],"category_scores_gemma":[0.1461698,0.0009309731,0.00392658,0.02533068,0.001946241,0.005674704,0.002041289,0.002604219,0.0008136546],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003835694,"about_ca_system_score_gemma":0.009774235,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002052528,"about_ca_topic_score_gemma":0.00521722,"domain_scores_codex":[0.9481152,0.02043302,0.0205452,0.003749637,0.006429287,0.0007276945],"domain_scores_gemma":[0.6197821,0.3067401,0.04344099,0.005296349,0.02138031,0.003360095],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.003028767,0.0001742918,0.01659804,0.1579324,0.00447361,0.0002686632,0.0007527164,0.0009308481,0.001122551,0.005115185,0.02558442,0.7840185],"study_design_scores_gemma":[0.00243626,0.002889697,0.08237986,0.518221,0.02131353,0.003352565,0.002225851,0.001462337,0.00123817,0.009580722,0.354623,0.0002770686],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003571183,0.9864949,0.0004498059,0.007050012,0.0001483922,0.0001604313,0.001001438,0.00002287961,0.001101008],"genre_scores_gemma":[0.03817774,0.9481397,0.003223181,0.007202922,0.0006474805,0.0006026911,0.001710145,0.00006204604,0.0002342062],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9950286,"threshold_uncertainty_score":0.3902063,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.133950559731472,"score_gpt":0.4006495831297068,"score_spread":0.2666990233982348,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}