{"id":"W3197159314","doi":"10.1002/exp.20210005","title":"Nanozyme for tumor therapy: Surface modification matters","year":2021,"lang":"en","type":"review","venue":"Exploration","topic":"Advanced Nanomaterials in Catalysis","field":"Materials Science","cited_by":428,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Youth Innovation Promotion Association of the Chinese Academy of Sciences; Youth Innovation Promotion Association; Chinese Academy of Sciences; National Natural Science Foundation of China","keywords":"Reactive oxygen species; Surface modification; Peroxidase; Catalysis; Nanotechnology; Computer science; Chemistry; Biochemical engineering; Materials science; Enzyme; Engineering; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005964816,0.0004076514,0.001261897,0.0001029036,0.0001795234,0.0002935303,0.000374327,0.0001766042,0.0001910266],"category_scores_gemma":[0.0001107744,0.0003578186,0.0003311821,0.0003374944,0.00005070528,0.0009099338,0.0000641848,0.00007290174,0.000488275],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002175528,"about_ca_system_score_gemma":0.0002161356,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000054805,"about_ca_topic_score_gemma":0.000001393113,"domain_scores_codex":[0.9975707,0.0002884259,0.0008190534,0.0007505972,0.0002746369,0.0002965652],"domain_scores_gemma":[0.9979385,0.0002378962,0.000818504,0.000765847,0.0001831799,0.0000561213],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005483581,0.0002250619,1.622636e-7,0.01086726,0.0001435589,0.00001184501,0.0006764165,0.0008780793,0.1851538,0.002200895,0.01411157,0.7856765],"study_design_scores_gemma":[0.0001553984,0.00002924349,2.309339e-8,0.001374605,0.0001471833,0.000008120536,0.00004434299,0.00002061093,0.04181238,0.0003916684,0.9556282,0.0003882504],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005991124,0.9661087,0.02986292,0.0001464693,0.001619665,0.001600108,0.0004076442,0.000175757,0.00001885124],"genre_scores_gemma":[0.00001270861,0.9811407,0.01293032,0.0001212091,0.0003914379,0.001264489,0.003723514,0.0001122992,0.0003033068],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9415166,"threshold_uncertainty_score":0.9998874,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1645062526205202,"score_gpt":0.3882975079783151,"score_spread":0.2237912553577949,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}