{"id":"W3197159314","doi":"10.1002/exp.20210005","title":"Nanozyme for tumor therapy: Surface modification matters","year":2021,"lang":"en","type":"review","venue":"Exploration","topic":"Advanced Nanomaterials in Catalysis","field":"Materials Science","cited_by":428,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Youth Innovation Promotion Association of the Chinese Academy of Sciences; Youth Innovation Promotion Association; Chinese Academy of Sciences; National Natural Science Foundation of China","keywords":"Reactive oxygen species; Surface modification; Peroxidase; Catalysis; Nanotechnology; Computer science; Chemistry; Biochemical engineering; Materials science; Enzyme; Engineering; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003358007,0.0008352451,0.0007527482,0.001185543,0.0001630828,0.0006107111,0.0004403644,0.00111376,0.002522661],"category_scores_gemma":[0.0002451195,0.0002468071,0.0004103671,0.001145388,0.0002993482,0.0008334205,0.0003654595,0.001326032,0.00131467],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003970539,"about_ca_system_score_gemma":0.0004786525,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005069987,"about_ca_topic_score_gemma":0.0007565104,"domain_scores_codex":[0.9998755,0.00002021568,0.00000999771,0.00002840902,0.00005241108,0.00001332329],"domain_scores_gemma":[0.9999255,0.00002878719,0.00001193844,0.000003540688,0.00002319659,0.000007063249],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000701352,0.0001551825,0.0001423445,0.02090715,0.00009439189,0.0004453122,0.00009525386,0.001044434,0.03621979,0.01413958,0.03383064,0.8928557],"study_design_scores_gemma":[0.00001662436,0.0001790556,0.0004357473,0.001493277,0.00005605208,0.0009606782,0.00004187024,0.0003013226,0.006075534,0.002526615,0.9878947,0.00001850453],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000465372,0.9959008,0.0006156499,0.0003052744,0.0005534572,0.00001052445,0.00001337571,0.00001018938,0.002125337],"genre_scores_gemma":[0.004033632,0.9920237,0.0005056158,0.0003650587,0.0002899603,0.00002076368,0.0000272697,0.000003250447,0.002730733],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002522661,"threshold_uncertainty_score":0.008439124,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1645062526205202,"score_gpt":0.3882975079783151,"score_spread":0.2237912553577949,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}