{"id":"W3197163648","doi":"10.3390/cells10092284","title":"Preimplantation Genetic Testing for Aneuploidy Improves Live Birth Rates with In Vitro Produced Bovine Embryos: A Blind Retrospective Study","year":2021,"lang":"en","type":"article","venue":"Cells","topic":"Prenatal Screening and Diagnostics","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"L'Alliance Boviteq","funders":"Biotechnology and Biological Sciences Research Council","keywords":"Aneuploidy; Biology; Embryo; Embryo transfer; Andrology; In vitro fertilisation; Pregnancy; Pregnancy rate; Live birth; SNP genotyping; Chromosome; Genetics; Gynecology; Genotyping; Genotype; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003117429,0.0002559335,0.000331484,0.001123866,0.0002382826,0.0004663893,0.0003233326,0.0003481853,0.0006880904],"category_scores_gemma":[0.006403533,0.0001966313,0.0003241585,0.0005625391,0.0004295263,0.0002281238,0.0002901279,0.0002331899,0.0002487165],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003086419,"about_ca_system_score_gemma":0.0002493787,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001627837,"about_ca_topic_score_gemma":0.00146396,"domain_scores_codex":[0.9978554,0.0007731744,0.0003370068,0.0004759118,0.000465593,0.00009299028],"domain_scores_gemma":[0.9940892,0.002552674,0.001499513,0.0007944184,0.0008576725,0.0002064636],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001311428,0.0001561961,0.9648327,0.0001141771,0.0001483581,0.0006916485,0.0004307406,0.0001543675,0.01110769,0.00005583202,0.0001251915,0.02087166],"study_design_scores_gemma":[0.00002959438,0.002715484,0.9818544,0.00004181257,0.0003525496,0.004115762,0.0002374376,0.0005388258,0.008130998,0.00003866471,0.001918672,0.00002573089],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955584,0.001801318,0.001625031,0.00001381433,0.000006377855,0.00005842312,0.0003239614,0.0000111863,0.0006015143],"genre_scores_gemma":[0.9976785,0.0007523107,0.0008137204,0.00002447174,0.00000814336,0.00002096017,0.000385495,0.000006385734,0.0003101897],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003117429,"threshold_uncertainty_score":0.0164867,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02297704706506559,"score_gpt":0.276317695307733,"score_spread":0.2533406482426674,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}