{"id":"W3197199162","doi":"10.1182/blood.2021010745","title":"<i>HLF</i> expression defines the human hematopoietic stem cell state","year":2021,"lang":"en","type":"article","venue":"Blood","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Maisonneuve-Rosemont; Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"Stem cell; Biology; Haematopoiesis; Progenitor cell; Cord blood; Transplantation; Bone marrow; Cell biology; Population; Hematopoietic stem cell; Immunology; Cancer research; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001605511,0.0001613863,0.0002476103,0.00003250742,0.0001527217,0.00003497827,0.000100552,0.0000691608,0.0001871877],"category_scores_gemma":[0.000006838497,0.0001101159,0.0001037575,0.0001804158,0.00004541336,0.00004303846,0.00003515685,0.0001706286,0.0001498448],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001074637,"about_ca_system_score_gemma":0.00008780316,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006928676,"about_ca_topic_score_gemma":0.000004753956,"domain_scores_codex":[0.9986985,0.00009112217,0.0003184444,0.0002844451,0.0003547999,0.0002526512],"domain_scores_gemma":[0.9990769,0.0001236028,0.00007823382,0.0005115055,0.00009939552,0.0001103393],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001827039,0.0007944318,0.01196148,0.0009773321,0.00005060075,0.0006439661,0.002602453,0.000004634524,0.9813861,0.0002740895,0.001049982,0.0002366945],"study_design_scores_gemma":[0.00258809,0.00005820208,0.002532345,0.0003487204,0.0002660217,0.0006181856,0.0006894953,0.000004483118,0.9910455,0.0002144743,0.001501609,0.0001329089],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9826505,0.001149675,0.0003543576,0.0004583441,0.00009292748,0.0002843509,0.00001084494,0.00009821761,0.01490081],"genre_scores_gemma":[0.9942733,0.0001170962,0.0005761247,0.000425739,0.00007896368,0.00003445506,0.00004093704,0.00003648524,0.004416874],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01162286,"threshold_uncertainty_score":0.4490396,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01757478314824478,"score_gpt":0.2479258556332318,"score_spread":0.230351072484987,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}