{"id":"W3197226589","doi":"","title":"A Cohesin Traffic Pattern Genetically Linked to Gene Regulation","year":2021,"lang":"en","type":"preprint","venue":"HAL (Le Centre pour la Communication Scientifique Directe)","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"","keywords":"Cohesin; CTCF; Enhancer; Chromatin; Biology; RNA polymerase II; Transcription (linguistics); Genetics; Chromosome conformation capture; Cell biology; Gene; Transcription factor; Promoter; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001078318,0.0002113404,0.0003072705,0.0007654889,0.0002710207,0.0007692464,0.0002302324,0.0006436485,0.002997874],"category_scores_gemma":[0.0005791843,0.0001882874,0.0001484498,0.0004346344,0.0003915199,0.0002662483,0.0003889083,0.0004370252,0.0005033574],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005352647,"about_ca_system_score_gemma":0.0002031734,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008237452,"about_ca_topic_score_gemma":0.000887928,"domain_scores_codex":[0.9998622,0.00001171961,0.00000732507,0.00005960339,0.00003226715,0.00002691931],"domain_scores_gemma":[0.9990646,0.0002859319,0.0002269729,0.0001175684,0.0001195484,0.0001853358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001434895,0.0000155065,0.001850116,0.0000119108,0.00000626471,0.00009902469,0.00001751641,0.0001652559,0.9959733,0.0004544622,0.00004714794,0.001215978],"study_design_scores_gemma":[0.00008252782,0.0002487293,0.2335414,0.00002164168,0.00007849,0.002530219,0.0002865278,0.01307481,0.7441093,0.004038297,0.001934596,0.00005339048],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961321,0.0002820879,0.002219602,0.0001105487,0.00001960395,0.000006731477,0.000272341,0.00008000253,0.0008769766],"genre_scores_gemma":[0.9973547,0.0001041115,0.0003925166,0.00002596797,0.00001013855,0.000006922213,0.0002441689,0.00001919417,0.001842245],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002997874,"threshold_uncertainty_score":0.0100289,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008160965908291606,"score_gpt":0.2117645225468402,"score_spread":0.2036035566385486,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}