{"id":"W3197264332","doi":"10.1136/jclinpath-2021-207906","title":"Gene of the month: <i>STK11</i>","year":2021,"lang":"en","type":"review","venue":"Journal of Clinical Pathology","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University Health Network; University of Toronto","funders":"","keywords":"STK11; Cancer research; Biology; Kinase; Germline mutation; Cancer; Protein kinase A; Mutation; Medicine; Immunology; Gene; Genetics; KRAS","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002711861,0.0006761051,0.0006259647,0.0009240148,0.0002717981,0.0009020563,0.0006700299,0.001106007,0.0278562],"category_scores_gemma":[0.001209138,0.00011572,0.0004343735,0.001219148,0.0005504843,0.0009490217,0.0005502504,0.001385219,0.02044626],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004856567,"about_ca_system_score_gemma":0.0008572834,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001717595,"about_ca_topic_score_gemma":0.001829291,"domain_scores_codex":[0.9998103,0.00002471531,0.0000247287,0.000039054,0.00007476586,0.00002660784],"domain_scores_gemma":[0.9996976,0.00008923237,0.00004962462,0.00001199558,0.00009810142,0.00005356345],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000180213,0.00001512029,0.0003510195,0.00298884,0.00003685829,0.0007628258,0.00004946069,0.0001068643,0.002382316,0.003929849,0.4392151,0.5499815],"study_design_scores_gemma":[0.000005664141,0.0000137291,0.0003574783,0.000343231,0.00001035802,0.001275217,0.00001014664,0.00001374907,0.000241193,0.000241229,0.9974834,0.000004728115],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001264336,0.9038749,0.001134838,0.01368861,0.03854232,0.00004273875,0.001162406,0.0002316346,0.04005819],"genre_scores_gemma":[0.01123042,0.7993103,0.001791847,0.01409905,0.01301355,0.0000584051,0.003019568,0.0002090279,0.1572678],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0278562,"threshold_uncertainty_score":0.09318829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2040199981424749,"score_gpt":0.4928200477560251,"score_spread":0.2888000496135502,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}