{"id":"W3197306464","doi":"10.1016/j.ajhg.2021.07.006","title":"Response to Hamosh et al.","year":2021,"lang":"en","type":"letter","venue":"The American Journal of Human Genetics","topic":"Genomics and Rare Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; Alberta Children's Hospital; University of Calgary","funders":"","keywords":"Rebuttal; Hum; Psychology; Disease; Dyad; Genetics; Epistemology; Philosophy; Biology; Medicine; Social psychology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002435845,0.0008827914,0.001338742,0.0008090205,0.003809283,0.003011788,0.001859012,0.03518722,0.009693698],"category_scores_gemma":[0.01707495,0.000592921,0.000896545,0.0006356463,0.002116609,0.002543354,0.001233931,0.02892143,0.009598839],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002850667,"about_ca_system_score_gemma":0.002939399,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004682131,"about_ca_topic_score_gemma":0.006998074,"domain_scores_codex":[0.9983017,0.0004482319,0.0001495892,0.0002552965,0.0005561445,0.0002889756],"domain_scores_gemma":[0.9959453,0.001824231,0.0002354523,0.0001212587,0.0009512179,0.0009225681],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004686702,0.00001695982,0.0002017725,0.00001991873,0.000005795846,0.001222032,0.00004383686,0.00002797095,0.00005683227,0.0006279415,0.9954345,0.002295643],"study_design_scores_gemma":[0.0001441444,0.00007549408,0.001320448,0.0002172666,0.00002788788,0.003918476,0.000501991,0.0005382525,0.0003247098,0.006035675,0.9868228,0.00007279629],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0003704532,0.0008145165,0.00007718221,0.9633344,0.03170741,0.00001842311,0.00008646083,0.00006097556,0.00353021],"genre_scores_gemma":[0.002811429,0.0004880861,0.000128928,0.9655383,0.02210666,0.00003807891,0.00004826565,0.00002440643,0.008815933],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.03518722,"threshold_uncertainty_score":0.03242868,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01292044024345829,"score_gpt":0.2820472299798359,"score_spread":0.2691267897363777,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}