{"id":"W3197489461","doi":"10.3390/cells10092322","title":"Biosynthesis of the Novel Endogenous 15-Lipoxygenase Metabolites N-13-Hydroxy-octodecadienoyl-ethanolamine and 13-Hydroxy-octodecadienoyl-glycerol by Human Neutrophils and Eosinophils","year":2021,"lang":"en","type":"article","venue":"Cells","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Impact; Université Laval; Institut universitaire de cardiologie et de pneumologie de Québec","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Université Laval","keywords":"Ethanolamine; Lipoxygenase; Chemistry; Endocannabinoid system; Biochemistry; Monoacylglycerol lipase; Ethanolamines; Glycerol; Lipid signaling; Hydrolysis; Linoleic acid; Arachidonate 5-lipoxygenase; Arachidonic acid; Stereochemistry; Enzyme; Fatty acid; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001657809,0.0002581663,0.0001725785,0.0001121121,0.00008657797,0.0002323591,0.00008424824,0.000203471,0.0007274928],"category_scores_gemma":[0.0001270948,0.0001151315,0.0002299531,0.00008251651,0.0001089014,0.000210509,0.0001881661,0.0002451445,0.0003137609],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001415823,"about_ca_system_score_gemma":0.0001774683,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007798278,"about_ca_topic_score_gemma":0.001460069,"domain_scores_codex":[0.9998863,0.0000247748,0.00001178671,0.00002672117,0.00002125194,0.0000291492],"domain_scores_gemma":[0.9999492,0.000008954637,0.00001088002,0.000007123956,0.0000114864,0.0000123522],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000215132,0.00001244411,0.0006751665,0.00003008767,0.000004454716,0.0001186824,0.00002655625,0.00003507101,0.9975361,0.00004215213,0.00001248845,0.001291802],"study_design_scores_gemma":[0.00003626935,0.000482151,0.01779926,0.00001617783,0.00002927869,0.0005621326,0.000132647,0.0006014347,0.9779158,0.0000673118,0.0023491,0.000008527575],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919996,0.004272245,0.002454795,0.00006803915,0.00001894228,0.00005609834,0.0004627527,0.00001011763,0.0006572586],"genre_scores_gemma":[0.9927219,0.001873151,0.002468828,0.00005702537,0.00001014144,0.00004671511,0.0007633054,0.000005503805,0.002053444],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007798278,"threshold_uncertainty_score":0.002433717,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01852345209525155,"score_gpt":0.2459716100662946,"score_spread":0.227448157971043,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}