{"id":"W3197515132","doi":"10.1200/po.21.00153","title":"Upfront Adjuvant Immunotherapy of Replication Repair–Deficient Pediatric Glioblastoma With Chemoradiation-Sparing Approach","year":2021,"lang":"en","type":"article","venue":"JCO Precision Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"","keywords":"Medicine; Adjuvant; Glioblastoma; Replication (statistics); Immunotherapy; Oncology; Internal medicine; Cancer research; Cancer; Virology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001480465,0.0002663506,0.0005242382,0.0002069317,0.0001895894,0.0002812379,0.0002815534,0.0002240008,0.001132321],"category_scores_gemma":[0.0001722929,0.00008639397,0.0003488543,0.0001976027,0.0001539759,0.0002796212,0.0002482739,0.0007121161,0.0002332117],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004180328,"about_ca_system_score_gemma":0.0005197107,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007228195,"about_ca_topic_score_gemma":0.001797724,"domain_scores_codex":[0.9999315,0.000008288072,0.000004244638,0.00001821924,0.00001158687,0.00002622402],"domain_scores_gemma":[0.9999493,0.00000738018,0.00001032618,0.00001078846,0.00000810684,0.00001399922],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.008128772,0.001836863,0.014169,0.0009781317,0.0004451044,0.002690623,0.0003103583,0.006990762,0.2688537,0.005474134,0.01167701,0.6784455],"study_design_scores_gemma":[0.007032103,0.04365048,0.09192431,0.0007987308,0.003825199,0.03360995,0.0006913794,0.02748963,0.4972675,0.01179349,0.2817493,0.000167993],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.957076,0.02134195,0.01190802,0.001155894,0.0003866585,0.0002528508,0.0006607838,0.0005055779,0.006712403],"genre_scores_gemma":[0.985974,0.005594791,0.005290587,0.0003953309,0.00006395169,0.0001588045,0.0009604586,0.00004194814,0.001520149],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001132321,"threshold_uncertainty_score":0.003787935,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01808639142601828,"score_gpt":0.2951753760971705,"score_spread":0.2770889846711523,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}