{"id":"W3197661862","doi":"10.1242/dev.199814","title":"Signalling pathways and transcriptional regulators orchestrating liver development and cancer","year":2021,"lang":"en","type":"review","venue":"Development","topic":"Liver physiology and pathology","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Terry Fox Research Institute","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Biology; Signalling; Transcription factor; Liver cancer; Induced pluripotent stem cell; Signal transduction; Cell biology; Stem cell; Cancer; Cancer research; Bioinformatics; Embryonic stem cell; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004339036,0.0009707189,0.001028125,0.001849284,0.000245038,0.001127762,0.0008831518,0.001019687,0.004110712],"category_scores_gemma":[0.0004284313,0.0002922024,0.0003293049,0.001940648,0.0005376685,0.001278976,0.000861169,0.001698892,0.004243487],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007001591,"about_ca_system_score_gemma":0.0008092653,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005673014,"about_ca_topic_score_gemma":0.001179945,"domain_scores_codex":[0.9998591,0.00002229468,0.00001979986,0.00002664449,0.0000529857,0.00001914423],"domain_scores_gemma":[0.9998348,0.00006337336,0.00002490433,0.000006187483,0.00004649299,0.00002423512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000100533,0.00004828012,0.0001516653,0.01279891,0.00006536207,0.0002314027,0.0000601965,0.0005253893,0.005333565,0.007852737,0.04321298,0.9296188],"study_design_scores_gemma":[0.000007101055,0.00003408601,0.0004196017,0.001610912,0.0000355111,0.0006565108,0.00002930961,0.00005583059,0.0005555197,0.002132543,0.9944512,0.00001183817],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007429365,0.9978599,0.0001669054,0.000214277,0.0002443818,0.00000333944,0.00002605864,0.00001111565,0.001399737],"genre_scores_gemma":[0.0004177666,0.9979346,0.00017674,0.0001719058,0.0001758916,0.00000574483,0.00005678851,0.000002419818,0.001058232],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004110712,"threshold_uncertainty_score":0.01375175,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.134469237651748,"score_gpt":0.3234907476556801,"score_spread":0.1890215100039321,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}