{"id":"W3197818806","doi":"10.1016/j.placenta.2021.07.166","title":"DISRUPTED PLACENTAL SYNCYTIAL DEVELOPMENT: AN EMERGING ROLE FOR SPHINGOLIPID MEDIATORS IN TUMOR NECROSIS FACTOR-ALPHA SIGNALING","year":2021,"lang":"en","type":"article","venue":"Placenta","topic":"Synthesis of Tetrazole Derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Women and Children’s Health Research Institute; University of Alberta","funders":"","keywords":"Sphingolipid; Tumor necrosis factor alpha; Cell biology; Alpha (finance); Biology; Signal transduction; Cancer research; Immunology; Psychology; Developmental psychology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001721967,0.0003832407,0.0004345298,0.0001270971,0.0002196834,0.0001365956,0.0004170116,0.0001386429,0.001403779],"category_scores_gemma":[0.000538194,0.0004366391,0.0001315177,0.0002304361,0.00005173128,0.0004266933,0.0001690252,0.0002618242,0.00002276514],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005453264,"about_ca_system_score_gemma":0.0003729462,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007310315,"about_ca_topic_score_gemma":0.000230443,"domain_scores_codex":[0.9975115,0.0000429925,0.0005981602,0.0007093964,0.0004236095,0.0007143213],"domain_scores_gemma":[0.9987242,0.0004165044,0.000194984,0.0003498158,0.00006953199,0.0002450219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002996075,0.0005412151,0.0892227,0.0002759063,0.000138369,0.00006795229,0.007840423,0.0000609956,0.8938037,0.00003360288,0.00008487998,0.00763064],"study_design_scores_gemma":[0.001773748,0.00001054667,0.005689462,0.0002199286,0.00002346998,0.00001463503,0.006143035,0.001651011,0.9797432,0.00003445227,0.004136339,0.0005601532],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982404,0.0002252577,0.00008238869,0.00008678536,0.0002737472,0.000157433,0.0001564033,0.0001717683,0.0006058405],"genre_scores_gemma":[0.9952473,0.000009573883,0.003684978,0.00008511727,0.0002778529,0.0000945824,0.0003722981,0.00009085437,0.0001374273],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08593951,"threshold_uncertainty_score":0.9998085,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02042643206950468,"score_gpt":0.2718289293073753,"score_spread":0.2514024972378706,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}