{"id":"W3197836405","doi":"10.1172/jci147076","title":"Immune response to intravenous immunoglobulin in patients with Kawasaki disease and MIS-C","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Kawasaki Disease and Coronary Complications","field":"Medicine","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Metropolitan University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; University of California, San Diego; National Institutes of Health; Novo Nordisk Fonden","keywords":"Kawasaki disease; Medicine; Immunology; Antibody; Immune system; Blockade; Disease; Immunoglobulin G; Intravenous Immunoglobulins; Innate immune system; Receptor; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000789999,0.00009606114,0.0003639184,0.0001110283,0.0000390427,0.00002257465,0.00006779474,0.00005536879,0.00003424962],"category_scores_gemma":[0.002603594,0.00007680313,0.00009215246,0.0002958237,0.00009807247,0.0001374547,0.00002571362,0.0002867774,0.000009539338],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005135439,"about_ca_system_score_gemma":0.0009461681,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000411975,"about_ca_topic_score_gemma":0.000002699964,"domain_scores_codex":[0.9981034,0.0002843411,0.00100767,0.0001693157,0.0003028087,0.0001324386],"domain_scores_gemma":[0.9978853,0.0003300593,0.0003186314,0.000252015,0.0005526972,0.0006613153],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01496661,0.0009797682,0.9729072,0.00003483522,0.00008830049,0.0002308435,0.0001622305,0.00004788722,0.001209866,0.00009160885,0.0002598045,0.00902107],"study_design_scores_gemma":[0.003708256,0.001214888,0.9928153,0.0004250492,0.0001510751,0.00002544812,0.00006392469,0.00003506938,0.0001362123,0.0006267219,0.0007149843,0.00008308746],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9879515,0.000458701,0.0001001579,0.01113607,0.00008892209,0.0002050125,0.000006271202,0.000006466447,0.00004692559],"genre_scores_gemma":[0.9950324,0.00004365909,0.002584061,0.002093744,0.0001147719,0.000004723931,0.00002265843,0.00001185312,0.00009216805],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0199081,"threshold_uncertainty_score":0.3131941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03426214972236977,"score_gpt":0.3383754572306101,"score_spread":0.3041133075082403,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}