{"id":"W3197836405","doi":"10.1172/jci147076","title":"Immune response to intravenous immunoglobulin in patients with Kawasaki disease and MIS-C","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Kawasaki Disease and Coronary Complications","field":"Medicine","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Metropolitan University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; University of California, San Diego; National Institutes of Health; Novo Nordisk Fonden","keywords":"Kawasaki disease; Medicine; Immunology; Antibody; Immune system; Blockade; Disease; Immunoglobulin G; Intravenous Immunoglobulins; Innate immune system; Receptor; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002782015,0.0003124466,0.0004113641,0.0003879378,0.0003208567,0.0003023654,0.0001574537,0.0004733778,0.001103856],"category_scores_gemma":[0.000891805,0.00009626889,0.0001545837,0.000357718,0.0001993397,0.000217276,0.0002428656,0.0003983213,0.0001215877],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003365736,"about_ca_system_score_gemma":0.0002429865,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006522009,"about_ca_topic_score_gemma":0.0006213111,"domain_scores_codex":[0.9997811,0.0000538214,0.00002301868,0.00004532592,0.0000359835,0.00006075798],"domain_scores_gemma":[0.9996254,0.00007535018,0.0001150058,0.00001620278,0.00004464848,0.0001233405],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001501778,0.0001650744,0.9797764,0.0000804509,0.0000429727,0.005887174,0.0001992702,0.0000734202,0.003963193,0.00006438995,0.0004883448,0.007757498],"study_design_scores_gemma":[0.0001103855,0.00139894,0.974821,0.00003472716,0.00007718773,0.02017733,0.0003501167,0.0002909961,0.001024587,0.00007955376,0.001626497,0.000008650409],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977609,0.0008804947,0.00009560442,0.000142346,0.00001700381,0.00002946002,0.00008646584,0.000006892346,0.0009807652],"genre_scores_gemma":[0.9993623,0.0001587614,0.0001011584,0.00009407372,0.00003524216,0.00001400707,0.0001160935,9.506314e-7,0.0001173076],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001103856,"threshold_uncertainty_score":0.003692746,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03426214972236977,"score_gpt":0.3383754572306101,"score_spread":0.3041133075082403,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}