{"id":"W3197871386","doi":"10.1016/j.powtec.2021.08.088","title":"Delayed sustained drug release from electrostatic powder coated tablets with ultrafine polymer blends","year":2021,"lang":"en","type":"article","venue":"Powder Technology","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"","keywords":"Coating; Materials science; Polymer; Methyl cellulose; Ethyl cellulose; Chemical engineering; Scanning electron microscope; Hydroxypropyl cellulose; Dissolution; Enteric coating; Dissolution testing; Polymer blend; Curing (chemistry); Film coating; Composite material; Cellulose; Copolymer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003347879,0.0005193194,0.0007323075,0.0003816351,0.0004097722,0.00004961026,0.0004966981,0.0008720912,0.003533038],"category_scores_gemma":[0.0001683799,0.0004891482,0.0001189114,0.001516548,0.0005367489,0.0001877,0.0001624404,0.00162242,0.0004819745],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001578845,"about_ca_system_score_gemma":0.0006241919,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004648217,"about_ca_topic_score_gemma":0.0006449222,"domain_scores_codex":[0.9963469,0.000565797,0.0006575648,0.000915831,0.000286052,0.001227854],"domain_scores_gemma":[0.9977462,0.0004617109,0.0002641641,0.0007527189,0.000464395,0.000310771],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003830577,0.002169552,0.0257495,0.0002104438,0.003670819,0.006494747,0.002777898,0.0002655786,0.8587323,0.01875336,0.06767053,0.009674657],"study_design_scores_gemma":[0.006028702,0.0003532867,0.0002307842,0.00004880956,0.0005981211,0.0005634053,0.003580901,0.001310237,0.8749535,0.002137212,0.1093025,0.0008925443],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9692289,0.00670996,0.0003093089,0.01678346,0.0007832094,0.0005131746,0.0003051491,0.001021359,0.004345499],"genre_scores_gemma":[0.98289,0.0002676494,0.0001577743,0.00439493,0.0001529,0.0001247475,0.0004958985,0.00008179223,0.01143432],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04163194,"threshold_uncertainty_score":0.999756,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02399671745721076,"score_gpt":0.3257155248208261,"score_spread":0.3017188073636153,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}