{"id":"W3198002660","doi":"10.21203/rs.3.rs-827822/v1","title":"Exosomal hsa_circ_0007047 Attenuates Pos-myocardial Infarction Remodeling by Promoting Angiogenesis via miR-1178-3p/PDPK1 Axis","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"Circular RNAs in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"Guangzhou University; Guangzhou University of Chinese Medicine; National Science Foundation","keywords":"Angiogenesis; Exosome; Microvesicles; Ventricular remodeling; Myocardial infarction; microRNA; Fibrosis; Cell biology; Biology; Cancer research; Internal medicine; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003113998,0.0003720761,0.0005136484,0.0003401014,0.0003786271,0.0008292517,0.0002589019,0.0006062817,0.01018521],"category_scores_gemma":[0.0005068246,0.0003330371,0.0003703755,0.000249574,0.0004592157,0.000342314,0.0003873505,0.001330477,0.0026941],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003039745,"about_ca_system_score_gemma":0.0004468914,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006314288,"about_ca_topic_score_gemma":0.0007545986,"domain_scores_codex":[0.9996823,0.0000375947,0.00002308512,0.00009189763,0.00008670906,0.0000782894],"domain_scores_gemma":[0.9998524,0.00002852254,0.00003878092,0.0000224481,0.0000200066,0.00003785244],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006414302,0.0003981639,0.00505858,0.0005870423,0.000228025,0.0004275443,0.0001391237,0.0006759084,0.9459983,0.002890113,0.007939895,0.02924299],"study_design_scores_gemma":[0.0006704246,0.00125658,0.04204747,0.00005686827,0.0003938014,0.001093794,0.000184521,0.006918608,0.8954037,0.001955773,0.0499656,0.00005287392],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.958679,0.006585282,0.009748403,0.001312358,0.001490273,0.00009170383,0.007340638,0.001640959,0.01311142],"genre_scores_gemma":[0.9771128,0.001271263,0.003076008,0.0007649667,0.0001649089,0.000137252,0.006004012,0.0003736641,0.0110952],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01018521,"threshold_uncertainty_score":0.03407294,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02895081104011924,"score_gpt":0.3403784053531771,"score_spread":0.3114275943130578,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}