{"id":"W3198007733","doi":"10.3390/ijms22179616","title":"Mice with Whole-Body Disruption of AMPK-Glycogen Binding Have Increased Adiposity, Reduced Fat Oxidation and Altered Tissue Glycogen Dynamics","year":2021,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Health and Medical Research Council; Natural Sciences and Engineering Research Council of Canada; Australian Catholic University","keywords":"Glycogen; AMPK; Internal medicine; Endocrinology; AMP-activated protein kinase; Protein kinase A; Glycogen synthase; Biology; Glucose uptake; Skeletal muscle; Chemistry; Insulin; Phosphorylation; Biochemistry; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001376842,0.001013371,0.0005162135,0.001009267,0.0002186401,0.0004885331,0.0003211514,0.0005693541,0.003203831],"category_scores_gemma":[0.0001255261,0.0004186663,0.0003034897,0.0005068021,0.000644304,0.0002993836,0.0003991233,0.001061433,0.0007086972],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003456581,"about_ca_system_score_gemma":0.0001804627,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003966446,"about_ca_topic_score_gemma":0.0009519064,"domain_scores_codex":[0.9998068,0.00001453323,0.0000268463,0.00008025019,0.00004371016,0.00002782422],"domain_scores_gemma":[0.9996402,0.00002627921,0.0002185244,0.00002016329,0.00001189008,0.00008283238],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000192056,0.00005430995,0.0005313328,0.00003887395,0.00001436839,0.00008919476,0.00001380757,0.00005496623,0.9976326,0.0001344809,0.00007038003,0.00117351],"study_design_scores_gemma":[0.0001781119,0.001208179,0.05959421,0.00005247759,0.0001609054,0.003331562,0.0001489742,0.00115495,0.926872,0.0004566386,0.006800039,0.00004196618],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9873346,0.0008936047,0.005954621,0.0001994746,0.00005848413,0.00004191064,0.003689769,0.0004741918,0.001353339],"genre_scores_gemma":[0.9735469,0.002227048,0.008981101,0.0002591608,0.0000301394,0.000188967,0.004293245,0.0003394728,0.01013383],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003203831,"threshold_uncertainty_score":0.01071793,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009453072138993723,"score_gpt":0.2790542993868435,"score_spread":0.2696012272478498,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}