{"id":"W3198279249","doi":"10.1186/s13567-021-00986-y","title":"Chronic wasting disease: a cervid prion infection looming to spillover","year":2021,"lang":"en","type":"review","venue":"Veterinary Research","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Genome Alberta; University of Alberta; Alberta Agriculture and Forestry; Genome Canada","keywords":"Chronic wasting disease; Biology; Enzootic; Transmission (telecommunications); Disease; Outbreak; Livestock; Virology; Scrapie; Ecology; Prion protein; Medicine; Virus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008597009,0.0003444204,0.0005658821,0.0002751619,0.0002922541,0.0001649764,0.0003943052,0.0002810828,0.0002371736],"category_scores_gemma":[0.0005547829,0.0003335493,0.000477723,0.0005862744,0.00005510983,0.000007891571,0.001562277,0.0004720844,0.0001480253],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002715203,"about_ca_system_score_gemma":0.001072677,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001286234,"about_ca_topic_score_gemma":0.000003889159,"domain_scores_codex":[0.9968079,0.0007267081,0.0003780091,0.00093018,0.000462903,0.0006943141],"domain_scores_gemma":[0.9983876,0.00005964919,0.00009630319,0.0008332532,0.0001818987,0.0004413192],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003238339,0.00003628309,0.00003296433,0.0171569,0.00008734078,0.0001506074,0.000005236568,0.000008113029,0.00272104,0.000007998627,0.0009879372,0.9787732],"study_design_scores_gemma":[0.0001099886,0.0006563058,0.00003396085,0.0159888,0.0000667741,0.00007074348,0.00000332613,0.000009842964,0.00006993963,0.000002842854,0.9826291,0.0003584172],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002064942,0.9962679,0.0001451067,0.00003817601,0.0002229147,0.001028358,0.00005489084,0.00002245829,0.0001553278],"genre_scores_gemma":[0.0004666508,0.9958475,0.0001504411,0.00002037415,0.001747378,0.0004429404,0.0005066741,0.00009394111,0.0007240935],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9816411,"threshold_uncertainty_score":0.9999117,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2278520517895647,"score_gpt":0.4892471884028328,"score_spread":0.2613951366132681,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}