{"id":"W3198292876","doi":"10.3389/fcvm.2021.739045","title":"Brain-Derived Neurotrophic Factor Mitigates the Association Between Platelet Dysfunction and Cognitive Impairment","year":2021,"lang":"en","type":"article","venue":"Frontiers in Cardiovascular Medicine","topic":"Apelin-related biomedical research","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Université du Québec à Montréal; Baycrest Hospital; Université de Montréal; Montreal Heart Institute","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Fondation Institut de Cardiologie de Montréal; Université de Montréal; Canada Research Chairs; Institut de Cardiologie de Montréal; Canada Foundation for Innovation","keywords":"Brain-derived neurotrophic factor; Platelet activation; Internal medicine; Montreal Cognitive Assessment; Neurotrophic factors; Platelet; Cognitive decline; Endocrinology; Medicine; Psychology; Dementia; Disease; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001745673,0.0002519428,0.0009492395,0.0002431053,0.0001361326,0.0000216937,0.0001019949,0.0003224011,0.000100022],"category_scores_gemma":[0.004976474,0.0001698572,0.0003246534,0.0008121583,0.000390398,0.00007294174,0.0001085814,0.00101746,0.00001434547],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004199201,"about_ca_system_score_gemma":0.0002038268,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008775902,"about_ca_topic_score_gemma":0.000003724766,"domain_scores_codex":[0.9961354,0.0006262422,0.0004595688,0.0005719364,0.001682414,0.0005244879],"domain_scores_gemma":[0.9980633,0.0007389418,0.000100255,0.0004135206,0.0003630881,0.0003209214],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005718427,0.000170958,0.7336844,0.0004514581,0.01443164,0.002414712,0.002333379,0.00001179335,0.005397927,0.000006928866,0.02107798,0.2194469],"study_design_scores_gemma":[0.008589112,0.0004804945,0.9717336,0.0005788248,0.001222755,0.0001135909,0.001434806,0.0002294647,0.001547173,0.0001375344,0.01375158,0.000181064],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9207475,0.0484427,0.005063994,0.02310389,0.0009368636,0.001133146,0.00002780797,0.0000666221,0.0004775183],"genre_scores_gemma":[0.9943515,0.001929163,0.0002195636,0.001900894,0.0009042238,0.0000554486,0.0002166965,0.0000418903,0.0003806389],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2380492,"threshold_uncertainty_score":0.6926575,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01582321478717531,"score_gpt":0.2648478350073757,"score_spread":0.2490246202202004,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}