{"id":"W3198411056","doi":"10.1093/ecco-jcc/jjab152","title":"Is Also the Patient Ready for Switching from Intravenous to Subcutaneous Biologics?","year":2021,"lang":"en","type":"letter","venue":"Journal of Crohn s and Colitis","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Takeda Canada; Celltrion","keywords":"Vedolizumab; Medicine; Inflammatory bowel disease; Crohn's disease; Subcutaneous injection; Disease; Intensive care medicine; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003516778,0.000266827,0.000771209,0.0000775124,0.0002182481,0.0001041481,0.0003056175,0.0009418558,0.000441599],"category_scores_gemma":[0.0002121768,0.0001527974,0.000309348,0.00007335449,0.0001227656,0.00002546441,0.0001128227,0.001414201,0.000007137752],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004453717,"about_ca_system_score_gemma":0.0001094915,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001624772,"about_ca_topic_score_gemma":0.00002206703,"domain_scores_codex":[0.9982035,0.0003311154,0.0006834405,0.0002913635,0.00007414877,0.0004164873],"domain_scores_gemma":[0.9978459,0.001033008,0.0004966971,0.0002467349,0.0003308538,0.00004683245],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008029637,0.0000507617,0.00001777804,0.0000344106,0.0007322853,0.0009579319,0.0004702815,1.427844e-7,0.001278385,0.00007848577,0.9198391,0.07573752],"study_design_scores_gemma":[0.0002976328,0.001436001,0.001338828,0.0001682232,0.0003364594,0.001696802,0.0001907868,8.223156e-7,0.002312163,0.002696168,0.9893039,0.0002221712],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.08837847,0.02276842,0.001342528,0.8804165,0.003985204,0.0006840478,0.001983858,0.0000142068,0.0004267901],"genre_scores_gemma":[0.04192889,0.001862449,0.0031349,0.9483775,0.002514079,0.00001892764,0.0001096311,0.00004341496,0.002010183],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.07551534,"threshold_uncertainty_score":0.7264454,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03467721961218399,"score_gpt":0.2884944352905215,"score_spread":0.2538172156783375,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}