{"id":"W3198465542","doi":"10.1016/j.cgh.2021.09.001","title":"Impact of HBeAg on Hepatocellular Carcinoma Risk During Oral Antiviral Treatment in Patients With Chronic Hepatitis B","year":2021,"lang":"en","type":"article","venue":"Clinical Gastroenterology and Hepatology","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network","funders":"Merck Sharp and Dohme; Ipsen; Seoul National University Hospital; Ministry of Science, ICT and Future Planning; Bayer HealthCare; Janssen Pharmaceuticals; National Research Foundation of Korea; Gilead Sciences; Roche; GlaxoSmithKline; AbbVie; Bristol-Myers Squibb","keywords":"Medicine; Hepatocellular carcinoma; Internal medicine; Gastroenterology; HBeAg; Hazard ratio; Cirrhosis; Cohort; Entecavir; Proportional hazards model; Confidence interval; Hepatitis B virus; HBsAg; Immunology; Lamivudine; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000844127,0.0002710848,0.0004483853,0.0005044686,0.0004216605,0.000877184,0.0002143449,0.0005783359,0.001257151],"category_scores_gemma":[0.00389223,0.0002437536,0.001065913,0.0008931937,0.0002505501,0.0007010251,0.0004113006,0.0009249755,0.0001469334],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004171068,"about_ca_system_score_gemma":0.0004994077,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006814693,"about_ca_topic_score_gemma":0.007442671,"domain_scores_codex":[0.9994749,0.0002514328,0.0000472222,0.00005716415,0.00007411828,0.00009523467],"domain_scores_gemma":[0.9980837,0.0007732672,0.000627981,0.0001033698,0.0001308647,0.0002808621],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001404551,0.00007052223,0.9958917,0.0000241764,0.0002535794,0.00003646126,0.00005017973,0.00003163221,0.00008830114,0.00001327967,0.00003654524,0.002098965],"study_design_scores_gemma":[0.00002395721,0.0003670798,0.9988839,0.00001332952,0.0002020753,0.000058105,0.0001693911,0.00009738305,0.00004855674,0.00001927297,0.0001127359,0.000004087798],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971431,0.001791403,0.0000265915,0.00009660982,0.00001429033,0.000005606418,0.0001433465,0.000001401213,0.0007775976],"genre_scores_gemma":[0.9992668,0.0003576142,0.00002552918,0.00003441859,0.00002226393,0.000002890004,0.0001312693,0.00000101687,0.0001582223],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006814693,"threshold_uncertainty_score":0.01355004,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02186113127382442,"score_gpt":0.3110917264997121,"score_spread":0.2892305952258877,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}