{"id":"W3198671937","doi":"10.1161/circulationaha.121.057063","title":"Amplatzer Amulet Left Atrial Appendage Occluder Versus Watchman Device for Stroke Prophylaxis (Amulet IDE): A Randomized, Controlled Trial","year":2021,"lang":"en","type":"article","venue":"Circulation","topic":"Atrial Fibrillation Management and Outcomes","field":"Medicine","cited_by":389,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Biosense Webster; National Institutes of Health; Daiichi-Sankyo; Amgen; Edwards Lifesciences; Cardinal Health; InfraRedx; Regeneron Pharmaceuticals; Medicure; Boston Scientific Corporation; Daiichi Sankyo Europe; Sanofi; European Commission; Pfizer; CSL Behring","keywords":"Atrial fibrillation; Left atrial appendage occlusion; Stroke (engine); Appendage; Randomized controlled trial; Atrial Appendage","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00253959,0.001486416,0.004721799,0.000607754,0.0005276383,0.001492761,0.0008796892,0.002573191,0.008362597],"category_scores_gemma":[0.004140408,0.0007109146,0.002672152,0.0005885103,0.001077393,0.001307306,0.0004790205,0.002611451,0.0007399959],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005837771,"about_ca_system_score_gemma":0.001240911,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009329355,"about_ca_topic_score_gemma":0.001382891,"domain_scores_codex":[0.9985867,0.0007841031,0.0001502041,0.0002404172,0.0001071501,0.0001314719],"domain_scores_gemma":[0.9984173,0.0007588139,0.0003928649,0.00008625512,0.000100025,0.0002447999],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9870338,0.001781141,0.0003738202,0.001607456,0.001581554,0.000028392,0.00002488805,0.0001119181,0.0004124372,0.0001291073,0.0004228112,0.006492761],"study_design_scores_gemma":[0.9909,0.00733931,0.0004161534,0.00008049938,0.0007633447,0.00001327206,0.000007049967,0.0001380088,0.00004801019,0.00008128068,0.0002083283,0.000004802651],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9404857,0.0385812,0.00148017,0.002143636,0.002544214,0.008622314,0.001671054,0.0001874518,0.004284311],"genre_scores_gemma":[0.961125,0.01342267,0.002818013,0.00247094,0.002243946,0.01351583,0.001229361,0.00002681776,0.003147384],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008362597,"threshold_uncertainty_score":0.02797568,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06118803575898777,"score_gpt":0.3467271195957758,"score_spread":0.285539083836788,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}