{"id":"W3198755743","doi":"10.1093/humrep/deab194","title":"PGT-A for recurrent pregnancy loss: evidence is growing but the issue is not resolved","year":2021,"lang":"en","type":"letter","venue":"Human Reproduction","topic":"Prenatal Screening and Diagnostics","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Reproductive medicine; Guideline; Pregnancy; Gynecology; Family medicine; Human reproduction; Medicine; Genetic counseling; Clinical Practice; Genetic testing; Reproduction; Biology; Pathology; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005159015,0.0003732401,0.00051525,0.000111175,0.0004141858,0.0001077462,0.0002736569,0.0005049258,0.0002660543],"category_scores_gemma":[0.002844232,0.000290966,0.0003448397,0.0001983441,0.000137557,0.000170968,0.0001446858,0.001516153,0.00007241272],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001546688,"about_ca_system_score_gemma":0.0001170819,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001782821,"about_ca_topic_score_gemma":0.000007429151,"domain_scores_codex":[0.9967462,0.0001245901,0.000537361,0.001484034,0.0006659686,0.0004418491],"domain_scores_gemma":[0.9966513,0.0003764997,0.0003241659,0.002124551,0.0004573994,0.00006609956],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001061836,0.00004666896,0.0001353051,0.001274075,0.0001213856,0.0001505186,0.0005877471,8.991042e-7,0.0006925378,0.00001716488,0.972365,0.02450252],"study_design_scores_gemma":[0.0004405269,0.0004892623,0.0006996591,0.009820585,0.0006389281,0.0001734276,0.00007947131,0.0000151791,0.02378979,0.0002167737,0.9632837,0.0003526776],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.003399142,0.0263667,0.0003555845,0.9644724,0.002833953,0.00177516,0.00007971788,0.0002005242,0.000516827],"genre_scores_gemma":[0.01374144,0.004087615,0.002306999,0.7601905,0.08166822,0.001107358,0.002267544,0.0003105433,0.1343197],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.2042818,"threshold_uncertainty_score":0.9999542,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1213604423040745,"score_gpt":0.3435436734496462,"score_spread":0.2221832311455717,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}