{"id":"W3198824431","doi":"10.1083/jcb.202102146","title":"The cell biology of fertilization: Gamete attachment and fusion","year":2021,"lang":"en","type":"review","venue":"The Journal of Cell Biology","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Centre National de la Recherche Scientifique; Institut National de Recherche et de Sécurité; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; Université de Paris; Bill and Melinda Gates Foundation","keywords":"Gamete; Human fertilization; Zygote; Biology; Zona pellucida; Sperm; Acrosome reaction; In vitro fertilisation; Acrosome; Oocyte; Cell biology; Evolutionary biology; Genetics; Embryo; Embryogenesis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002284591,0.0002463409,0.001606998,0.00008991844,0.0001250825,0.000004030509,0.0002945031,0.0004381199,0.0000812915],"category_scores_gemma":[0.000404638,0.00009922041,0.0003604327,0.0001731656,0.0007507984,0.00001459679,0.0001765614,0.0006616642,0.00000605138],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004755061,"about_ca_system_score_gemma":0.0003498077,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003912325,"about_ca_topic_score_gemma":0.000001012543,"domain_scores_codex":[0.9966274,0.001768738,0.001076805,0.0002345571,0.00007628919,0.0002161851],"domain_scores_gemma":[0.996551,0.001013784,0.001350904,0.0005350712,0.0004786669,0.00007058748],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001630687,0.0002820619,0.0003894722,0.003698546,0.000658131,0.00001468045,0.0002208495,4.877094e-7,0.01842057,0.0001099302,0.0007646357,0.97381],"study_design_scores_gemma":[0.0003974801,0.001170535,0.0002686829,0.0007124846,0.001304231,0.0003230699,0.00006427734,0.000001244321,0.003656779,0.0001709377,0.9918359,0.00009435776],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005851524,0.991642,0.00008497375,0.0003638896,0.0006573177,0.0003717036,0.00001080124,0.000003226101,0.00101459],"genre_scores_gemma":[0.006287994,0.9927325,0.00007437651,0.00007774258,0.0003017604,0.000003670219,0.0000352394,0.00001249471,0.0004742082],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9910713,"threshold_uncertainty_score":0.4046091,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05698305549667731,"score_gpt":0.3646450331377869,"score_spread":0.3076619776411096,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}