{"id":"W3198888530","doi":"10.1128/iai.00225-21","title":"Small Intestinal Levels of the Branched Short-Chain Fatty Acid Isovalerate Are Elevated during Infection with Heligmosomoides polygyrus and Can Promote Helminth Fecundity","year":2021,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Parasites and Host Interactions","field":"Immunology and Microbiology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of Victoria","funders":"Canada Foundation for Innovation; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Biology; Heligmosomoides polygyrus; Fecundity; Helminths; Isovalerate; Helminthiasis; Anthelmintic; Immunology; Microbiology; Zoology; Biochemistry; Environmental health","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007963154,0.000281294,0.0002194942,0.0003723882,0.0001568595,0.0003418351,0.00008040734,0.0002910902,0.001007503],"category_scores_gemma":[0.0001622999,0.0001478565,0.0001623946,0.0002116427,0.0002256587,0.0001904271,0.0002251504,0.0005255011,0.0001710314],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001972488,"about_ca_system_score_gemma":0.0001466902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001174408,"about_ca_topic_score_gemma":0.001908396,"domain_scores_codex":[0.9998958,0.00001384121,0.000005956848,0.00002053934,0.00001874557,0.00004510615],"domain_scores_gemma":[0.9996467,0.00002382623,0.0001644803,0.00001168171,0.00002259015,0.0001307371],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001402384,0.00006194113,0.009230654,0.00004463495,0.00002001085,0.0001487675,0.00007258668,0.00002074368,0.987955,0.00002613983,0.00003135655,0.0009858338],"study_design_scores_gemma":[0.00003254519,0.001855209,0.7107936,0.0000252575,0.00007435254,0.0004174905,0.0004375335,0.0003136811,0.2849042,0.0001281304,0.001000332,0.00001760995],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987483,0.0004311316,0.0001524865,0.0000284483,0.000009025713,0.000005669242,0.0002482142,0.00001283473,0.0003639019],"genre_scores_gemma":[0.9981461,0.0002660788,0.0001699279,0.00002929583,0.000005103008,0.00001168105,0.0002567817,0.000003984873,0.001111073],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001174408,"threshold_uncertainty_score":0.003370404,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02979785515945869,"score_gpt":0.2592922199281136,"score_spread":0.2294943647686549,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}