{"id":"W3198888530","doi":"10.1128/iai.00225-21","title":"Small Intestinal Levels of the Branched Short-Chain Fatty Acid Isovalerate Are Elevated during Infection with Heligmosomoides polygyrus and Can Promote Helminth Fecundity","year":2021,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Parasites and Host Interactions","field":"Immunology and Microbiology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of Victoria","funders":"Canada Foundation for Innovation; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Biology; Heligmosomoides polygyrus; Fecundity; Helminths; Isovalerate; Helminthiasis; Anthelmintic; Immunology; Microbiology; Zoology; Biochemistry; Environmental health","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001734817,0.0001833108,0.0002465986,0.00006939072,0.0006557828,0.0000420324,0.00004994187,0.000141356,0.0001148137],"category_scores_gemma":[0.0001891359,0.0001389393,0.00006353154,0.0002646877,0.0002437721,0.0001159336,0.0001134018,0.0005519093,0.000004413856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004796562,"about_ca_system_score_gemma":0.00006130057,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003008187,"about_ca_topic_score_gemma":0.008139003,"domain_scores_codex":[0.9989188,0.0003868755,0.0002418876,0.0002184525,0.00003080692,0.0002031878],"domain_scores_gemma":[0.9992614,0.00007046367,0.0001662941,0.0002446293,0.000228677,0.00002856755],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001057133,0.0001146425,0.335056,0.00004740112,0.0001218425,0.000002475444,0.0003062059,0.000007666726,0.6627297,0.00002587226,0.000003317359,0.001479158],"study_design_scores_gemma":[0.0003925714,0.0001178469,0.5438647,0.0001258767,0.00003908196,0.0007377675,0.00008915299,0.000007279695,0.4543927,0.00002774521,0.0001139656,0.00009131576],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983087,0.0004019065,0.0003079544,0.0001612475,0.0003589291,0.0002000446,0.00005632703,0.00005751894,0.0001473829],"genre_scores_gemma":[0.9993312,0.0001999516,0.00003441551,0.00004794751,0.00001840662,0.00001569003,0.00002836195,0.00001179674,0.0003122651],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2088086,"threshold_uncertainty_score":0.566578,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02979785515945869,"score_gpt":0.2592922199281136,"score_spread":0.2294943647686549,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}