{"id":"W3198895413","doi":"10.1016/j.bcp.2021.114752","title":"Carbon monoxide as an emerging pharmacological tool to improve lung and liver transplantation protocols","year":2021,"lang":"en","type":"review","venue":"Biochemical Pharmacology","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"London Health Sciences Centre; Western University","funders":"","keywords":"Carboxyhemoglobin; Carbon monoxide; Transplantation; Lung; Organ transplantation; Hypoxia (environmental); Lung transplantation; Oxygen transport; Hemoglobin; Liver transplantation; Medicine; Tissue hypoxia; Oxygen; Pharmacology; Chemistry; Intensive care medicine; Anesthesia; Surgery; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003319909,0.000726848,0.00121383,0.0001244341,0.000086567,0.00005249586,0.0004570663,0.001018699,0.0001645496],"category_scores_gemma":[0.00007053733,0.0006810466,0.0003636762,0.0002257237,0.000123353,0.000008979977,0.000307145,0.0005412485,0.00001516165],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009631557,"about_ca_system_score_gemma":0.0004212733,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002140964,"about_ca_topic_score_gemma":0.000001155469,"domain_scores_codex":[0.9963213,0.0004674918,0.0007551759,0.001527863,0.0002173967,0.0007107409],"domain_scores_gemma":[0.9986979,0.00005456462,0.0002233732,0.0003615552,0.0001180914,0.0005444773],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002388553,0.0002510287,0.00000214769,0.003998102,0.0004379004,0.00036277,0.00003747747,0.000001316197,0.8777144,0.00001454406,0.01428585,0.1026556],"study_design_scores_gemma":[0.0008705155,0.0004285652,0.000001579475,0.0004481028,0.001241961,0.0002840584,0.00001038132,0.00005194202,0.3216756,0.000003860447,0.6741534,0.0008300148],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.08615072,0.9030401,0.0000505152,0.00005489918,0.0003781059,0.009893727,0.0001200821,0.00005994866,0.0002518614],"genre_scores_gemma":[0.001860653,0.9809818,0.0004927373,0.001104105,0.001453198,0.01292463,0.000798275,0.0001147467,0.0002698454],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6598676,"threshold_uncertainty_score":0.9995641,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02799622768025908,"score_gpt":0.3824033616909476,"score_spread":0.3544071340106885,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}