{"id":"W3198965035","doi":"10.1182/bloodadvances.2021004916","title":"Haploidentical vs sibling, unrelated, or cord blood hematopoietic cell transplantation for acute lymphoblastic leukemia","year":2021,"lang":"en","type":"article","venue":"Blood Advances","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Ottawa Hospital; Princess Margaret Cancer Centre","funders":"Cancer Moonshot; National Cancer Institute; Office of Naval Research; National Heart, Lung, and Blood Institute; Biomedical Advanced Research and Development Authority; National Institutes of Health; National Center for Advancing Translational Sciences; Health Resources and Services Administration; bluebird bio; Astellas Pharma; Angiocrine Bioscience; National Institute of Allergy and Infectious Diseases; Celgene; Actinium Pharmaceuticals; Moonshot Research and Development Program; Bristol-Myers Squibb; Amgen","keywords":"Medicine; Hazard ratio; Internal medicine; Umbilical cord; Cyclophosphamide; Transplantation; Gastroenterology; Hematopoietic stem cell transplantation; Human leukocyte antigen; Graft-versus-host disease; Hematopoietic cell; Lymphoblastic Leukemia; Cord blood; Oncology; Retrospective cohort study; Leukemia; Haematopoiesis; Immunology; Chemotherapy; Confidence interval; Antigen; Stem cell; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001605533,0.0003538287,0.0006414068,0.0001570524,0.0001656449,0.00006432936,0.0001370694,0.0002253929,0.0002825368],"category_scores_gemma":[0.0001122731,0.0003076859,0.0002293973,0.0005003264,0.00009915084,0.0002662054,0.00001460479,0.0002008026,0.00008529496],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005827952,"about_ca_system_score_gemma":0.0005961313,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005838084,"about_ca_topic_score_gemma":0.00004251661,"domain_scores_codex":[0.9975095,0.0000609823,0.0007198795,0.0006596157,0.0005147388,0.0005352158],"domain_scores_gemma":[0.998241,0.0007000634,0.0001688661,0.0003490855,0.0002702995,0.0002707012],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02534056,0.007963534,0.0442152,0.04763605,0.005472422,0.03132231,0.007349915,0.0009767894,0.8124992,0.008176828,0.001074191,0.007973049],"study_design_scores_gemma":[0.02110304,0.001940758,0.002297934,0.001786669,0.01393923,0.01089115,0.0006313812,0.000515499,0.94327,0.000909851,0.002029167,0.0006853178],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.943997,0.003446367,0.04623389,0.0004138822,0.0007248254,0.001311529,0.0001676402,0.0003315868,0.003373326],"genre_scores_gemma":[0.958132,0.006982126,0.02832253,0.0004931624,0.0002486891,0.0002147823,0.0005634233,0.0001149092,0.004928437],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1307709,"threshold_uncertainty_score":0.9999375,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01435071129726823,"score_gpt":0.2901177079337284,"score_spread":0.2757669966364602,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}