{"id":"W3198971774","doi":"10.1038/s41569-021-00608-2","title":"Minor hypertrophic cardiomyopathy genes, major insights into the genetics of cardiomyopathies","year":2021,"lang":"en","type":"review","venue":"Nature Reviews Cardiology","topic":"Cardiomyopathy and Myosin Studies","field":"Medicine","cited_by":123,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"Canadian Institutes of Health Research; Fondation Leducq; Amsterdam University Medical Centers; Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centers; Heart Rhythm Society","keywords":"Genome-wide association study; Hypertrophic cardiomyopathy; Genetics; Mendelian inheritance; Gene; Cardiomyopathy; Medicine; Biology; Single-nucleotide polymorphism; Internal medicine; Genotype; Heart failure","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","metaepi_broad","research_integrity"],"consensus_categories":["metaepi_narrow","research_integrity"],"category_scores_codex":[0.001858436,0.001603134,0.01792756,0.0005674869,0.0003258362,0.00003523749,0.0008617927,0.002850036,0.0000157494],"category_scores_gemma":[0.001065728,0.0009136219,0.009474705,0.001789177,0.0009116116,0.00005062269,0.0009248574,0.003366767,0.00007873394],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003195627,"about_ca_system_score_gemma":0.001297235,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002217275,"about_ca_topic_score_gemma":0.00001023462,"domain_scores_codex":[0.990842,0.003405788,0.002531353,0.001591955,0.0007881824,0.0008407414],"domain_scores_gemma":[0.9935324,0.0007553261,0.001205245,0.003400518,0.0008440441,0.0002624655],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002133627,0.00003003918,0.0001034297,0.03875504,0.004554981,0.0009863987,0.0002441655,0.0000013798,0.00001990045,0.0003458635,0.008130184,0.9468073],"study_design_scores_gemma":[0.0004438997,0.0001968976,0.00006143715,0.01357426,0.02429189,0.005694181,0.0001043087,3.251589e-7,0.00001329492,0.00003244415,0.9548484,0.0007386722],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006046754,0.9894907,0.00007219815,0.0001312359,0.003456052,0.003974481,0.00007932638,0.00007437752,0.002661114],"genre_scores_gemma":[0.0001748189,0.9918041,0.0008185928,0.0003480892,0.004742366,0.001075385,0.0004572058,0.0001911673,0.0003882492],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9467182,"threshold_uncertainty_score":0.9996716,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03660941895423265,"score_gpt":0.336125403049887,"score_spread":0.2995159840956543,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}