{"id":"W3199001556","doi":"10.1111/dom.14551","title":"Gastrointestinal tolerability of once‐weekly semaglutide 2.4 mg in adults with overweight or obesity, and the relationship between gastrointestinal adverse events and weight loss","year":2021,"lang":"en","type":"article","venue":"Diabetes Obesity and Metabolism","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":162,"is_retracted":false,"has_abstract":true,"ca_institutions":"LMC Diabetes & Endocrinology (Canada); McMaster University; York University","funders":"","keywords":"Semaglutide; Weight loss; Tolerability; Overweight; Adverse effect; Medicine; Obesity; Weight management; Gastrointestinal system; Anti obesity; Internal medicine; Endocrinology; Diabetes mellitus; Type 2 diabetes","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00341366,0.0002847627,0.0006668907,0.000332978,0.0001246345,0.0003503773,0.0001535775,0.0003361023,0.0009483818],"category_scores_gemma":[0.00411719,0.0002059457,0.001225698,0.0004681201,0.0001519126,0.0003421438,0.0002102691,0.0005273367,0.00008675921],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001969464,"about_ca_system_score_gemma":0.0002244048,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006839729,"about_ca_topic_score_gemma":0.001553561,"domain_scores_codex":[0.9990574,0.000454084,0.0001427233,0.0001227624,0.0001780071,0.00004502511],"domain_scores_gemma":[0.9966718,0.001093517,0.001871948,0.00008990311,0.0001633378,0.000109498],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.03908636,0.0004769834,0.8825613,0.001503116,0.007675272,0.0001591649,0.0001437271,0.0004636811,0.003476681,0.00004215351,0.000359167,0.06405239],"study_design_scores_gemma":[0.0009750359,0.006725115,0.9880619,0.00009349179,0.002469849,0.00028704,0.00004315003,0.000453045,0.0003937522,0.00003791601,0.0004513388,0.000008425486],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9872109,0.01149518,0.0002955598,0.0001251968,0.00002380921,0.00006119486,0.0002858303,0.00001077302,0.0004916526],"genre_scores_gemma":[0.997865,0.001348105,0.0002668358,0.00011633,0.00003814487,0.00003933268,0.0001805995,0.000002322122,0.0001433565],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00341366,"threshold_uncertainty_score":0.01805341,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01349681993986193,"score_gpt":0.2352660898053299,"score_spread":0.2217692698654679,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}