{"id":"W3199065741","doi":"10.3390/cells10102517","title":"The Dual Role of Autophagy in Crizotinib-Treated ALK+ ALCL: From the Lymphoma Cells Drug Resistance to Their Demise","year":2021,"lang":"en","type":"review","venue":"Cells","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Autophagy; Crizotinib; Context (archaeology); Cancer research; Programmed cell death; Biology; Cell biology; Chemistry; Medicine; Lung cancer; Apoptosis; Oncology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004988516,0.0005995298,0.001949477,0.00008591566,0.000143812,0.00005649939,0.0006951542,0.0003070023,0.0002855758],"category_scores_gemma":[0.00009535881,0.0003161281,0.0007810175,0.0006685344,0.0001705692,0.00003342318,0.0001808919,0.0003776235,0.000178081],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001631611,"about_ca_system_score_gemma":0.0007689518,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001519277,"about_ca_topic_score_gemma":0.00009779165,"domain_scores_codex":[0.9967433,0.000621019,0.001027074,0.0006708044,0.0004190858,0.0005187829],"domain_scores_gemma":[0.9957338,0.00180026,0.000441142,0.001654566,0.000138498,0.0002317079],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002649867,0.0005906069,0.00001762538,0.00207293,0.001099368,0.0004894579,0.001994343,0.000002732411,0.002039569,0.0002359914,0.03748364,0.9537088],"study_design_scores_gemma":[0.0007666606,0.00002616487,0.00006722021,0.009508357,0.0006720262,0.000005458334,0.0002930663,0.000004490362,0.03003684,0.0001507353,0.9581895,0.0002794773],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004962316,0.9899066,0.000002153856,0.0001819963,0.0003851432,0.001440473,0.0003743602,0.00005017536,0.002696779],"genre_scores_gemma":[0.001368931,0.9888726,0.00007439455,0.0005131523,0.0003771693,0.0001776551,0.0002078312,0.0001162093,0.008292054],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9534293,"threshold_uncertainty_score":0.9999291,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01756461777162798,"score_gpt":0.2895706695321788,"score_spread":0.2720060517605508,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}