{"id":"W3199122731","doi":"10.1016/j.ydbio.2021.09.001","title":"Human retinal model systems: Strengths, weaknesses, and future directions","year":2021,"lang":"en","type":"review","venue":"Developmental Biology","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Foundation Fighting Blindness; Damon Runyon Cancer Research Foundation","keywords":"Retinal; Retina; Biology; Neuroscience; Retinal regeneration; Human disease; Retinal degeneration; Strengths and weaknesses; Cell type; Laminar organization; Anatomy; Cell; Psychology; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002446818,0.001272665,0.002101427,0.002106157,0.0003255798,0.002082018,0.00177532,0.001879689,0.003356074],"category_scores_gemma":[0.00151638,0.0003534548,0.0006592363,0.001684963,0.001049838,0.002436663,0.001072776,0.003578945,0.001821943],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001239229,"about_ca_system_score_gemma":0.001706917,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001638364,"about_ca_topic_score_gemma":0.004024326,"domain_scores_codex":[0.9996724,0.00007668013,0.00003784787,0.00005051941,0.0001240319,0.00003848262],"domain_scores_gemma":[0.9990501,0.0004878567,0.00008427908,0.00003231214,0.0002352608,0.0001101596],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001986292,0.0001015647,0.0002837233,0.01297537,0.0001115012,0.0003172629,0.00005671604,0.0008039672,0.003771527,0.0150383,0.04836961,0.9179718],"study_design_scores_gemma":[0.00003735792,0.0001115086,0.0005633441,0.004062725,0.0001996083,0.001086966,0.00006592421,0.0002063515,0.0009214974,0.005825587,0.9868879,0.00003137138],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006795605,0.9985502,0.0002477247,0.000444046,0.0001590655,0.000003139901,0.00001802556,0.00000993716,0.0004998169],"genre_scores_gemma":[0.000427693,0.998412,0.0004534259,0.0002644926,0.000133114,0.000007735392,0.0000315199,0.000002654276,0.0002673048],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003356074,"threshold_uncertainty_score":0.01294017,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01878415256954434,"score_gpt":0.3063829152040494,"score_spread":0.287598762634505,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}