{"id":"W3199386151","doi":"10.3390/microorganisms9102004","title":"6S-Like scr3559 RNA Affects Development and Antibiotic Production in Streptomyces coelicolor","year":2021,"lang":"en","type":"article","venue":"Microorganisms","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Univerzite Jan Evangelista Purkyne v Ústí nad Labem; Univerzita Karlova v Praze","keywords":"Actinorhodin; Streptomyces coelicolor; Biology; Streptomyces; Mycelium; RNA; Gene; Secondary metabolite; Gene expression; Sigma factor; Strain (injury); Secondary metabolism; Genetics; Cell biology; Microbiology; Bacteria; Promoter; Biosynthesis; Botany","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009975533,0.0004422438,0.0002349866,0.0002912684,0.0001305474,0.0002398213,0.0001162485,0.0002010851,0.0009625473],"category_scores_gemma":[0.0001507487,0.0001128948,0.0003296545,0.0001509178,0.0002076303,0.00008491236,0.0001575647,0.0002557308,0.0003612198],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002491223,"about_ca_system_score_gemma":0.0001433369,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007002412,"about_ca_topic_score_gemma":0.000973572,"domain_scores_codex":[0.9997924,0.00003369457,0.00001605386,0.00005893831,0.00006554303,0.00003332375],"domain_scores_gemma":[0.9998066,0.00003536118,0.00007645543,0.00001849957,0.00001803026,0.00004512768],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002627751,0.000003250825,0.00008951185,0.000007604807,8.563693e-7,0.00003043463,0.000004393499,0.00001556653,0.9995098,0.00001021611,0.000004921049,0.0002972136],"study_design_scores_gemma":[0.000005827391,0.0003045034,0.01593449,0.000005644277,0.00001290935,0.0003091267,0.00003517995,0.000430653,0.9816886,0.00002545737,0.001241165,0.000006429851],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939963,0.0007874205,0.002837691,0.000076881,0.0000214551,0.00001803101,0.000903703,0.0001256559,0.001232841],"genre_scores_gemma":[0.9930897,0.0002655884,0.002864175,0.00005645625,0.00001182951,0.00001792733,0.001659801,0.00004024036,0.001994155],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009625473,"threshold_uncertainty_score":0.003220081,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01123257953672009,"score_gpt":0.2280844867744713,"score_spread":0.2168519072377512,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}