{"id":"W3199386151","doi":"10.3390/microorganisms9102004","title":"6S-Like scr3559 RNA Affects Development and Antibiotic Production in Streptomyces coelicolor","year":2021,"lang":"en","type":"article","venue":"Microorganisms","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Univerzite Jan Evangelista Purkyne v Ústí nad Labem; Univerzita Karlova v Praze","keywords":"Actinorhodin; Streptomyces coelicolor; Biology; Streptomyces; Mycelium; RNA; Gene; Secondary metabolite; Gene expression; Sigma factor; Strain (injury); Secondary metabolism; Genetics; Cell biology; Microbiology; Bacteria; Promoter; Biosynthesis; Botany","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001996926,0.0001735249,0.0002877591,0.0001031723,0.00009114189,0.00004307015,0.00004950366,0.0001120753,0.0001393385],"category_scores_gemma":[0.0001541752,0.0001428128,0.00002852053,0.0003577094,0.00006324237,0.00007405925,0.00008152788,0.0001833293,0.00005178858],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009373244,"about_ca_system_score_gemma":0.0001858121,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001673029,"about_ca_topic_score_gemma":0.0001062694,"domain_scores_codex":[0.9988457,0.00004365312,0.0002093968,0.0005115976,0.0001266362,0.0002630312],"domain_scores_gemma":[0.9995377,0.00001983144,0.00005591919,0.0002127585,0.00009003982,0.00008372623],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000389113,0.0001608642,0.002886629,0.0001927734,0.00003159936,0.0001215893,0.0003631634,1.529472e-7,0.9652585,0.000009790181,0.001942629,0.02899342],"study_design_scores_gemma":[0.0004918092,0.00005954308,0.03841703,0.0002237366,0.00003448564,0.0002686503,0.0002141146,8.426093e-7,0.9465732,0.0000074832,0.01354002,0.0001690624],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933426,0.001689799,0.000002921301,0.004013421,0.0003584068,0.0003406727,0.000002609706,0.00005102315,0.000198518],"genre_scores_gemma":[0.9914839,0.0001558418,0.005431805,0.0005930713,0.0001564743,5.622773e-7,0.00002930864,0.00002348466,0.002125601],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03553041,"threshold_uncertainty_score":0.5823738,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01123257953672009,"score_gpt":0.2280844867744713,"score_spread":0.2168519072377512,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}