{"id":"W3199494162","doi":"10.1681/asn.2021040561","title":"Human or Chimeric Monoclonal Anti-CD20 Antibodies for Children with Nephrotic Syndrome: A Superiority Randomized Trial","year":2021,"lang":"en","type":"article","venue":"Journal of the American Society of Nephrology","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Ministero della Salute","keywords":"Rituximab; Ofatumumab; Medicine; CD20; Nephrotic syndrome; Calcineurin; Internal medicine; Immunology; Randomized controlled trial; Gastroenterology; Pharmacology; Transplantation; Lymphoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005007301,0.001561502,0.003863286,0.0003804031,0.0004849709,0.001162421,0.0009762922,0.003225652,0.006695083],"category_scores_gemma":[0.005250078,0.0006378593,0.003604542,0.0004541185,0.001233485,0.001449855,0.0005629779,0.003151247,0.0007122213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009191297,"about_ca_system_score_gemma":0.001556621,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007741499,"about_ca_topic_score_gemma":0.001210565,"domain_scores_codex":[0.9973806,0.001639691,0.0002011187,0.0003638676,0.0001808558,0.0002338777],"domain_scores_gemma":[0.9971988,0.001189828,0.0006369961,0.0002358476,0.0002106127,0.0005278597],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9871968,0.00169771,0.0007418457,0.0008874142,0.002087501,0.00005438098,0.00002855386,0.0002160727,0.0008085031,0.0001967139,0.0007171116,0.005367418],"study_design_scores_gemma":[0.9839902,0.01365044,0.0005228212,0.00004317168,0.0008078484,0.00002940708,0.000006969961,0.0002588256,0.0001247745,0.0001194178,0.000438378,0.00000764765],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9476373,0.02017968,0.002443841,0.003273872,0.002881373,0.0168271,0.003148933,0.000197756,0.003410137],"genre_scores_gemma":[0.9566022,0.005381549,0.005205143,0.004244916,0.001768669,0.02040116,0.002104341,0.00004520013,0.004246793],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006695083,"threshold_uncertainty_score":0.02648145,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01621228310410201,"score_gpt":0.2963510896559289,"score_spread":0.2801388065518269,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}