{"id":"W3199541104","doi":"10.1016/j.phrs.2021.105883","title":"Application of carbon monoxide in kidney and heart transplantation: A novel pharmacological strategy for a broader use of suboptimal renal and cardiac grafts","year":2021,"lang":"en","type":"review","venue":"Pharmacological Research","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"London Health Sciences Centre; Western University","funders":"","keywords":"Transplantation; Kidney; Organ transplantation; Heme oxygenase; Medicine; Reperfusion injury; Cold storage; Kidney transplantation; Pharmacology; Heme; Heart transplantation; Ischemia; Chemistry; Internal medicine; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001177055,0.0002965161,0.001084821,0.0001677082,0.00004646164,0.00002702131,0.0001891173,0.0005216551,0.00001276296],"category_scores_gemma":[0.000267284,0.0002436384,0.0002588924,0.00034358,0.0003532895,0.000008167961,0.0001661378,0.0005063859,2.388438e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003591658,"about_ca_system_score_gemma":0.0004789827,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000867868,"about_ca_topic_score_gemma":0.00000560226,"domain_scores_codex":[0.9971511,0.0006399023,0.0006552217,0.0007627267,0.0003188411,0.0004721823],"domain_scores_gemma":[0.9986287,0.0004995295,0.0001434776,0.0001676686,0.0002586097,0.0003019511],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005762568,0.0004608211,0.0002045506,0.005550917,0.0003869847,0.00001940087,0.00002399868,0.00003185353,0.914241,0.0001166588,0.0005064256,0.07788112],"study_design_scores_gemma":[0.005071387,0.002458405,0.001184957,0.002109157,0.001730436,0.00008854616,0.00007652065,0.001419161,0.1618123,0.00005261248,0.8228495,0.001147063],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1133938,0.8832979,0.0002340943,0.00006641083,0.00004075588,0.002345968,0.0005560701,0.00000735413,0.00005770443],"genre_scores_gemma":[0.05363396,0.9438968,0.0007561814,0.00004356791,0.0001371691,0.001018396,0.0004268291,0.00002841189,0.00005871064],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.822343,"threshold_uncertainty_score":0.9935286,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1958081949856346,"score_gpt":0.4605680554775261,"score_spread":0.2647598604918914,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}