{"id":"W3199559230","doi":"10.1111/febs.16209","title":"Haem oxygenase limits <i>Mycobacterium marinum</i> infection‐induced detrimental ferrostatin‐sensitive cell death in zebrafish","year":2021,"lang":"en","type":"article","venue":"FEBS Journal","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Health and Medical Research Council; NSW Ministry of Health; University of Sydney","keywords":"Mycobacterium marinum; Zebrafish; HMOX1; Pathogen; Biology; Microbiology; Mycobacterium; Host (biology); Xiphophorus; Cell biology; Heme oxygenase; Heme; Gene; Genetics; Biochemistry; Bacteria; Enzyme; Fish <Actinopterygii>","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002945599,0.0002521987,0.0002399325,0.00009848882,0.0001455818,0.0001283891,0.000117269,0.0002183404,0.00008413084],"category_scores_gemma":[0.0001184464,0.0002631476,0.0002014648,0.0002088484,0.00002477867,0.00001787399,0.0001239707,0.0004380014,0.0000361401],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001022676,"about_ca_system_score_gemma":0.0003845524,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005687991,"about_ca_topic_score_gemma":0.0004250113,"domain_scores_codex":[0.9982486,0.0002332653,0.0004235056,0.0003997072,0.0002210834,0.0004738895],"domain_scores_gemma":[0.9990666,0.000019984,0.0001599887,0.0002631138,0.0002099407,0.0002803918],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000113493,0.0001932738,0.02085644,0.00001197637,0.00004644403,0.0005402081,0.00009425114,0.00002601218,0.9755335,0.000004977045,0.001977687,0.0006017657],"study_design_scores_gemma":[0.001457232,0.0002478266,0.06815968,0.00002954519,0.00002364803,0.000978668,0.0001940997,0.00002294531,0.9240693,0.0000333452,0.004481606,0.0003020453],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935009,0.0002425463,0.0002137086,0.0001752343,0.000595075,0.0001103359,0.00002996194,0.00001278754,0.005119383],"genre_scores_gemma":[0.9963111,0.0002550383,0.0007029512,0.0008640174,0.0006035743,0.000008272183,0.0001154019,0.00004176293,0.001097847],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05146412,"threshold_uncertainty_score":0.9999821,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01507966578347547,"score_gpt":0.2493680209487344,"score_spread":0.2342883551652589,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}