{"id":"W3199559230","doi":"10.1111/febs.16209","title":"Haem oxygenase limits <i>Mycobacterium marinum</i> infection‐induced detrimental ferrostatin‐sensitive cell death in zebrafish","year":2021,"lang":"en","type":"article","venue":"FEBS Journal","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Health and Medical Research Council; NSW Ministry of Health; University of Sydney","keywords":"Mycobacterium marinum; Zebrafish; HMOX1; Pathogen; Biology; Microbiology; Mycobacterium; Host (biology); Xiphophorus; Cell biology; Heme oxygenase; Heme; Gene; Genetics; Biochemistry; Bacteria; Enzyme; Fish <Actinopterygii>","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001442255,0.0003694649,0.0002477815,0.0003042177,0.0002667514,0.0003032615,0.0003117001,0.0005409486,0.001972289],"category_scores_gemma":[0.0001098991,0.0002111988,0.0003578147,0.00009648017,0.0004435741,0.0002552514,0.0003418361,0.0008112898,0.0006266533],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009697547,"about_ca_system_score_gemma":0.0004587802,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004769542,"about_ca_topic_score_gemma":0.008686708,"domain_scores_codex":[0.9998564,0.000009535031,0.00001112276,0.00004491738,0.00003875098,0.00003938664],"domain_scores_gemma":[0.9998736,0.00001475391,0.00004656979,0.00001379709,0.00001652411,0.00003463319],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005389253,0.000006829459,0.00008478719,0.00001894711,0.00000156157,0.0000274903,0.000013123,0.00002812799,0.9992538,0.00009496404,0.00004168255,0.00037484],"study_design_scores_gemma":[0.0000183999,0.0002609904,0.004344762,0.00001048966,0.00001192092,0.0001184452,0.00004799472,0.0006366537,0.9921378,0.00006107011,0.002343644,0.000007720188],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868284,0.001135045,0.005494078,0.0003421658,0.00008242413,0.00006810105,0.001165299,0.0002670643,0.004617322],"genre_scores_gemma":[0.981841,0.000672391,0.003380719,0.0001533775,0.000009315455,0.00009883512,0.0005920682,0.0000711194,0.01318114],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004769542,"threshold_uncertainty_score":0.009483516,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01507966578347547,"score_gpt":0.2493680209487344,"score_spread":0.2342883551652589,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}