{"id":"W3199590448","doi":"10.1200/jco.2020.39.28_suppl.296","title":"Real-world trends in EU4 and the UK in frontline (1L) maintenance (MT) for nonsquamous (NSQ) advanced non-small cell lung cancer (aNSCLC) without actionable mutations after introduction of immune checkpoint inhibitors.","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"GlaxoSmithKline (Canada)","funders":"","keywords":"Pemetrexed; Lung cancer; Medicine; Internal medicine; Oncology; Pembrolizumab; Tumor microenvironment; Cancer; Chemotherapy; Immunotherapy; Cisplatin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001496504,0.0001661365,0.0003935535,0.001852826,0.0002759592,0.001421722,0.0005432472,0.0005227129,0.002332937],"category_scores_gemma":[0.006170047,0.0002218418,0.0003585803,0.00423375,0.0003471263,0.0008859188,0.001444746,0.0003529268,0.0004709974],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002108393,"about_ca_system_score_gemma":0.00101535,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.03686923,"about_ca_topic_score_gemma":0.04051799,"domain_scores_codex":[0.9979854,0.0005220548,0.0004425166,0.0004157966,0.0003271643,0.0003070052],"domain_scores_gemma":[0.9897456,0.001167072,0.007509049,0.0002468275,0.0007723521,0.0005590185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001369219,0.00001125334,0.9967633,0.00003635756,0.00003336921,0.0001234858,0.0001930802,0.000077346,0.00006944162,0.00005512502,0.0006197474,0.001880403],"study_design_scores_gemma":[0.00001163334,0.00007722256,0.995746,0.0000530796,0.00002059703,0.0003692102,0.0006174932,0.0001802502,0.00009157314,0.00001572742,0.002810752,0.00000653392],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9872884,0.001144972,0.0001352255,0.0002683722,0.00001290777,0.00004122166,0.009840034,0.00001243558,0.001256328],"genre_scores_gemma":[0.9916292,0.0004841182,0.0002711383,0.0002150003,0.0000161411,0.00007749523,0.006838375,0.000009876984,0.0004586578],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03686923,"threshold_uncertainty_score":0.07330924,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02583623552032993,"score_gpt":0.3920085313243367,"score_spread":0.3661722958040068,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}