{"id":"W3199737834","doi":"10.1007/s12551-021-00831-8","title":"What keeps us ticking? Sinoatrial node mechano-sensitivity: the grandfather clock of cardiac rhythm","year":2021,"lang":"en","type":"review","venue":"Biophysical Reviews","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; British Heart Foundation; Heart and Stroke Foundation of Canada","keywords":"Sinoatrial node; Heartbeat; Automaticity; Rhythm; Neuroscience; Cardiac pacemaker; Biological clock; Cardiology; Cardiac cycle; Chronobiology; Heart Rhythm; Medicine; Heart rate; Internal medicine; Psychology; Circadian rhythm; Computer science; Blood pressure; Computer security","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00110547,0.0006184475,0.001470443,0.001141339,0.0002902145,0.001879543,0.0007705971,0.00148567,0.003799315],"category_scores_gemma":[0.002034306,0.000214947,0.0004227429,0.00111838,0.000976731,0.002515059,0.0008410176,0.002521697,0.002414434],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005157893,"about_ca_system_score_gemma":0.001277836,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000857935,"about_ca_topic_score_gemma":0.001475575,"domain_scores_codex":[0.9996511,0.00009280028,0.00004631351,0.00006633865,0.000108484,0.00003500621],"domain_scores_gemma":[0.9992065,0.00044974,0.00008015582,0.00002310941,0.0001805816,0.00005995824],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008831361,0.00002854575,0.0002818424,0.009052438,0.0000822177,0.0001690634,0.0001283171,0.0001416247,0.001427788,0.008459611,0.07038905,0.9097512],"study_design_scores_gemma":[0.00002460448,0.00008387544,0.0009544412,0.004516056,0.00008728938,0.0008862333,0.0001494494,0.00008518629,0.0002029134,0.006694391,0.9862908,0.00002468044],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005193176,0.9972103,0.00009471011,0.001401356,0.0007508972,0.000001463287,0.0000105325,0.000004963008,0.0004738666],"genre_scores_gemma":[0.000725107,0.9963965,0.0001319743,0.001002817,0.001232305,0.000003424765,0.00001509939,0.000002360566,0.0004903945],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003799315,"threshold_uncertainty_score":0.01270998,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04492232623479141,"score_gpt":0.3369999797173737,"score_spread":0.2920776534825822,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}