{"id":"W3199851505","doi":"10.1021/acs.jafc.1c03831","title":"In Vitro Metabolism of Azaspiracids 1–3 with a Hepatopancreatic Fraction from Blue Mussels (<i>Mytilus edulis</i>)","year":2021,"lang":"en","type":"article","venue":"Journal of Agricultural and Food Chemistry","topic":"Marine Toxins and Detection Methods","field":"Environmental Science","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"Norges Forskningsråd; Marine Biotechnology ERA-NET","keywords":"Mytilus; Shellfish; Blue mussel; Hepatopancreas; Mussel; Marine toxin; Shellfish poisoning; Biology; Biochemistry; Hydroxylation; Metabolic pathway; Metabolism; Chemistry; Chromatography; Toxin; Aquatic animal; Fishery; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001848593,0.0006440296,0.0002306773,0.0002050796,0.0001995144,0.0002405539,0.0001449171,0.0002339504,0.0006493299],"category_scores_gemma":[0.0001483955,0.0001841533,0.0003393586,0.0002594895,0.0001281109,0.000174205,0.0002140995,0.000380162,0.0003573033],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000229622,"about_ca_system_score_gemma":0.0002890173,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005248793,"about_ca_topic_score_gemma":0.006509088,"domain_scores_codex":[0.9998556,0.00002749883,0.0000179245,0.00003565747,0.00004087923,0.00002244588],"domain_scores_gemma":[0.9998966,0.00002402699,0.00002582746,0.00001473936,0.00002499062,0.00001372186],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001308698,0.00003360798,0.0005397096,0.00004115644,0.00001830526,0.00003940531,0.0000302851,0.0002053864,0.9978957,0.00001278733,0.00002106259,0.001031619],"study_design_scores_gemma":[0.00001861362,0.001090603,0.01428927,0.00001475886,0.00006457753,0.0001764195,0.00004592397,0.001056324,0.9814555,0.00002699025,0.001748548,0.0000125621],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916916,0.00209567,0.002131201,0.0000482516,0.00002511213,0.00007069977,0.001475555,0.00005095417,0.00241102],"genre_scores_gemma":[0.9854137,0.001510526,0.00425939,0.00005795909,0.0000128863,0.00003906992,0.00533439,0.00002562811,0.003346371],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005248793,"threshold_uncertainty_score":0.01043648,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00508285064638584,"score_gpt":0.1987884571224025,"score_spread":0.1937056064760166,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}