{"id":"W3199851505","doi":"10.1021/acs.jafc.1c03831","title":"In Vitro Metabolism of Azaspiracids 1–3 with a Hepatopancreatic Fraction from Blue Mussels (<i>Mytilus edulis</i>)","year":2021,"lang":"en","type":"article","venue":"Journal of Agricultural and Food Chemistry","topic":"Marine Toxins and Detection Methods","field":"Environmental Science","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"Norges Forskningsråd; Marine Biotechnology ERA-NET","keywords":"Mytilus; Shellfish; Blue mussel; Hepatopancreas; Mussel; Marine toxin; Shellfish poisoning; Biology; Biochemistry; Hydroxylation; Metabolic pathway; Metabolism; Chemistry; Chromatography; Toxin; Aquatic animal; Fishery; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001023415,0.0001080723,0.0002772907,0.00001033892,0.00003022976,0.00002028608,0.00006756973,0.00006252478,0.0005172463],"category_scores_gemma":[0.00003275019,0.00006214323,0.0000706678,0.0001985605,0.00004289958,0.0002303864,0.0000510105,0.0002137876,9.128059e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004056804,"about_ca_system_score_gemma":0.00001307958,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001011684,"about_ca_topic_score_gemma":0.00001972054,"domain_scores_codex":[0.9992064,0.0000350022,0.0003008716,0.0001303029,0.0002246449,0.0001027355],"domain_scores_gemma":[0.9994836,0.0000402592,0.0002738407,0.00007394192,0.00003789149,0.00009042279],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007153674,0.00007587638,0.002560989,0.00001852715,0.00003431311,0.00001445902,0.0001176313,0.00009743706,0.9950241,5.780287e-7,0.00006381219,0.001920765],"study_design_scores_gemma":[0.0005308993,0.00006444238,0.137481,0.00002500261,0.00005495227,0.0004029798,0.0005869665,0.00001288336,0.8598694,0.0001009223,0.0007792717,0.00009138243],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980246,0.0003963354,0.0001141367,0.000169217,0.00004951169,0.00002438855,0.000006206149,0.000003106741,0.001212498],"genre_scores_gemma":[0.9934465,0.0001022201,0.005975716,0.00004946268,0.000143855,0.000001449155,0.000002340986,0.000003456992,0.0002750065],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1351547,"threshold_uncertainty_score":0.5663484,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00508285064638584,"score_gpt":0.1987884571224025,"score_spread":0.1937056064760166,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}