{"id":"W3199922039","doi":"10.1002/anie.202111549","title":"Synthesis of a Tridecasaccharide Lipooligosaccharide Antigen from the Opportunistic Pathogen <i>Mycobacterium kansasii</i>","year":2021,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Bill and Melinda Gates Foundation","keywords":"Glycan; Mycobacterium kansasii; Pathogen; Mycobacterium tuberculosis; Microbiology; Glycosidic bond; Biology; Lipoarabinomannan; Mycobacterium; Human pathogen; Pathogenic organism; Glycosylation; Tuberculosis; Glycoprotein; Biochemistry; Bacteria; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001043513,0.0002071206,0.00009702302,0.0001302367,0.0001322703,0.0001334998,0.0001591809,0.0001987474,0.0008373605],"category_scores_gemma":[0.00008583859,0.00007484623,0.0001639641,0.0002156873,0.00009240483,0.000133211,0.0001705508,0.0002725293,0.0004092872],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002058307,"about_ca_system_score_gemma":0.0003412625,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008537105,"about_ca_topic_score_gemma":0.001352264,"domain_scores_codex":[0.9999343,0.000008926478,0.000004744335,0.00001102563,0.0000173202,0.00002363855],"domain_scores_gemma":[0.9999616,0.00000323587,0.00001156133,0.000005196121,0.000007944749,0.0000103713],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005747036,0.00006180569,0.0002493534,0.0001534544,0.00001212184,0.0001635231,0.00004044617,0.0005229455,0.9898825,0.0005802328,0.0001778081,0.008098292],"study_design_scores_gemma":[0.000008937871,0.0004876456,0.001573679,0.000007726811,0.000009890926,0.0002132649,0.00002357723,0.0005548095,0.9864575,0.00007613873,0.01057833,0.000008538782],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9621058,0.002006305,0.02237436,0.0002120183,0.0001035301,0.0001322821,0.0005099713,0.0001125547,0.0124432],"genre_scores_gemma":[0.9756631,0.001472727,0.01656262,0.00008589798,0.000008893323,0.00003869093,0.0006333049,0.00002190644,0.005512895],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008537105,"threshold_uncertainty_score":0.002801239,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01972808593880577,"score_gpt":0.2355282753196397,"score_spread":0.215800189380834,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}