{"id":"W3200022595","doi":"10.1007/s00125-021-05565-6","title":"Interactions between islets and regulatory immune cells in health and type 1 diabetes","year":2021,"lang":"en","type":"review","venue":"Diabetologia","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto General Hospital; University of Toronto; BC Children's Hospital; University Health Network; University of British Columbia","funders":"Breakthrough T1D Canada; Canadian Institutes of Health Research","keywords":"Immune system; Regeneration (biology); Immunology; Innate lymphoid cell; Context (archaeology); Biology; Pancreatic islets; Beta cell; Innate immune system; Cell type; Immune tolerance; Type 1 diabetes; Cell biology; Immunity; Diabetes mellitus; Cell; Islet; Endocrinology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007171677,0.001107637,0.001783971,0.001544006,0.0002141471,0.001282161,0.0007815344,0.001324927,0.002493258],"category_scores_gemma":[0.0007549202,0.0002648273,0.0003153711,0.001741011,0.0006402615,0.001256693,0.0008552786,0.002179435,0.001432964],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005803384,"about_ca_system_score_gemma":0.0008434694,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008133464,"about_ca_topic_score_gemma":0.001672778,"domain_scores_codex":[0.9998173,0.0000361069,0.00002419959,0.0000304218,0.00007025756,0.00002173957],"domain_scores_gemma":[0.999709,0.000144753,0.00004073859,0.000007799424,0.00005904529,0.00003872059],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001295257,0.00005967573,0.0001843087,0.01119879,0.00006065823,0.0001740233,0.00004111557,0.0003099846,0.001368181,0.003542841,0.04050883,0.9424222],"study_design_scores_gemma":[0.00004254029,0.0001051799,0.001115801,0.004328046,0.0001493368,0.001142364,0.00007155426,0.0001123567,0.0003211705,0.003678039,0.9889115,0.00002208252],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003495906,0.9992017,0.00005527854,0.0001606202,0.0002416197,0.000001252451,0.000006039194,0.000002693826,0.0002957356],"genre_scores_gemma":[0.0003317547,0.9986557,0.00007834217,0.0001510377,0.0004714683,0.00000282231,0.00001388867,5.970795e-7,0.000294352],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002493258,"threshold_uncertainty_score":0.008340776,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03265081049467464,"score_gpt":0.3037436121646164,"score_spread":0.2710928016699418,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}