{"id":"W3200055141","doi":"10.1186/s13063-021-05597-8","title":"Vaccine trials during a pandemic: potential approaches to ethical dilemmas","year":2021,"lang":"en","type":"letter","venue":"Trials","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"York University","keywords":"Medicine; Clinical trial; Pandemic; Public health; Public relations; Family medicine; Disease; Political science; Coronavirus disease 2019 (COVID-19); Infectious disease (medical specialty); Nursing; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.01940111,0.0007748257,0.006060171,0.0007765917,0.0001682471,0.000254257,0.0005853844,0.004077844,0.0006392658],"category_scores_gemma":[0.03377258,0.0005773929,0.001851609,0.000665603,0.00007039005,0.00005636904,0.0004608967,0.006887941,0.0004818912],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003321296,"about_ca_system_score_gemma":0.001289159,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001889018,"about_ca_topic_score_gemma":0.00001317156,"domain_scores_codex":[0.986227,0.00570222,0.003231645,0.001503879,0.002104803,0.001230408],"domain_scores_gemma":[0.9917142,0.005658864,0.0007565498,0.001416784,0.0002795245,0.0001740157],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.007159681,0.0001827846,0.0004842316,0.001941803,0.002157275,0.006862062,0.0003054398,0.000001616104,0.1169433,0.00003014052,0.8578848,0.006046888],"study_design_scores_gemma":[0.01117462,0.0003032484,0.0002498795,0.0006964952,0.001474086,0.0004172638,0.00004099058,0.00001076399,0.05138641,0.0002364089,0.9333786,0.0006311729],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.09212235,0.002519955,0.0006379855,0.8930014,0.002289734,0.007425482,0.0002326325,0.0004030226,0.001367464],"genre_scores_gemma":[0.005050077,0.00004533051,0.0004867466,0.9458301,0.04599247,0.000834075,0.0002112801,0.0002015008,0.001348402],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.08707227,"threshold_uncertainty_score":0.9996678,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.5117006991296441,"score_gpt":0.4532813793874896,"score_spread":0.05841931974215447,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}