{"id":"W3200055919","doi":"10.1016/j.crmeth.2021.100069","title":"Probe design for simultaneous, targeted capture of diverse metagenomic targets","year":2021,"lang":"en","type":"article","venue":"Cell Reports Methods","topic":"Genomics and Phylogenetic Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Metagenomics; Computational biology; Biology; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Computer science; Coronavirus disease 2019 (COVID-19); Genetics; Gene; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001911511,0.001168556,0.0008647121,0.0009554488,0.00050506,0.0009450287,0.0009262352,0.001430176,0.0060524],"category_scores_gemma":[0.002313748,0.0009797572,0.0007180588,0.0008461701,0.000639083,0.001108541,0.001307682,0.001547367,0.002820355],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006633761,"about_ca_system_score_gemma":0.0005281752,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00036014,"about_ca_topic_score_gemma":0.001048111,"domain_scores_codex":[0.9986545,0.0003203511,0.00007611822,0.0004603511,0.000320374,0.0001683577],"domain_scores_gemma":[0.9990482,0.0004424664,0.0001131918,0.0001288372,0.0001741211,0.00009324717],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002206642,0.00003529002,0.0002841923,0.0002072704,0.00001710822,0.00007079248,0.00008366481,0.00115209,0.9842926,0.001016457,0.0005637062,0.01205618],"study_design_scores_gemma":[0.00004336402,0.000294879,0.0005406094,0.00001779028,0.00001967457,0.0001335231,0.00004872122,0.006597336,0.9792861,0.0007327081,0.01225257,0.00003268175],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.1314115,0.001121871,0.8531945,0.0004529844,0.0001448735,0.001012414,0.002181223,0.006439392,0.004041159],"genre_scores_gemma":[0.2404172,0.0009842425,0.7424506,0.001003047,0.00004736833,0.00298582,0.003422468,0.001149624,0.007539619],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.0060524,"threshold_uncertainty_score":0.02024734,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02689087716054301,"score_gpt":0.3024788583841029,"score_spread":0.2755879812235599,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}