{"id":"W3200055919","doi":"10.1016/j.crmeth.2021.100069","title":"Probe design for simultaneous, targeted capture of diverse metagenomic targets","year":2021,"lang":"en","type":"article","venue":"Cell Reports Methods","topic":"Genomics and Phylogenetic Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Metagenomics; Computational biology; Biology; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Computer science; Coronavirus disease 2019 (COVID-19); Genetics; Gene; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007492545,0.0001883801,0.0003258258,0.00002601538,0.0000831028,0.00001054484,0.00009881453,0.0001542289,0.0000243655],"category_scores_gemma":[0.0006759055,0.0001777837,0.0002132986,0.00007139485,0.00006224895,5.633085e-7,0.0001456586,0.00005629711,4.927289e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001114287,"about_ca_system_score_gemma":0.0001986694,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009885621,"about_ca_topic_score_gemma":0.000003121274,"domain_scores_codex":[0.9985807,0.0002072914,0.0003973235,0.0004894911,0.0000790441,0.0002461333],"domain_scores_gemma":[0.9986903,0.0001336048,0.0002858532,0.0004883381,0.0003269044,0.00007500922],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004284249,0.00006510381,0.0002013993,0.00006343492,0.0001553636,0.00006768997,0.0001595737,0.003014935,0.9928346,0.000008033782,0.000772213,0.002614794],"study_design_scores_gemma":[0.0002174615,0.0001136167,0.0001137642,0.000003457197,0.0001170131,0.00005144917,0.0001933643,0.0001806462,0.9142206,0.0005746139,0.08402481,0.0001891643],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.1654563,0.02828022,0.8033706,0.0000407993,0.0008288831,0.000776327,0.00004242722,0.000007658109,0.001196782],"genre_scores_gemma":[0.4342244,0.0002755692,0.5628819,0.00006236589,0.00008134188,0.00003467088,0.00005901655,0.00002618716,0.002354542],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.2687681,"threshold_uncertainty_score":0.7249808,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02689087716054301,"score_gpt":0.3024788583841029,"score_spread":0.2755879812235599,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}