{"id":"W3200207529","doi":"10.1016/j.jaci.2021.09.009","title":"Comparative efficacy and safety of monoclonal antibodies and aspirin desensitization for chronic rhinosinusitis with nasal polyposis: A systematic review and network meta-analysis","year":2021,"lang":"en","type":"review","venue":"Journal of Allergy and Clinical Immunology","topic":"Sinusitis and nasal conditions","field":"Medicine","cited_by":225,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Joseph’s Healthcare Hamilton; Impact; McMaster University","funders":"","keywords":"Medicine; Omalizumab; Internal medicine; Dupilumab; Placebo; Mepolizumab; Nasal polyps; Nasal congestion; Adverse effect; Sinusitis; Randomized controlled trial; Asthma; Meta-analysis; Benralizumab; Relative risk; Confidence interval; Surgery; Immunoglobulin E; Nose; Immunology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005705485,0.002005099,0.01464077,0.002142631,0.0004287908,0.002177318,0.001821787,0.002296366,0.00381513],"category_scores_gemma":[0.01264352,0.001158061,0.02582253,0.002807454,0.0007238997,0.001335892,0.001250318,0.002046072,0.0002679594],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001589273,"about_ca_system_score_gemma":0.001582414,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004885401,"about_ca_topic_score_gemma":0.01350785,"domain_scores_codex":[0.9964439,0.001485288,0.001020314,0.0005105342,0.0003683298,0.0001715283],"domain_scores_gemma":[0.9931698,0.004728115,0.001379462,0.000220188,0.0003689489,0.0001335149],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.009763435,0.00008531805,0.00385982,0.2628829,0.7077759,0.000111016,0.0001019126,0.0004268132,0.0004075952,0.0001007788,0.000473361,0.01401119],"study_design_scores_gemma":[0.002789695,0.0005336503,0.004203271,0.008842801,0.9821723,0.00006262213,0.00005334205,0.0001234557,0.0000858131,0.0001075133,0.000999284,0.00002631312],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01424457,0.9844483,0.0003283225,0.0001079879,0.0001726971,0.0001664184,0.0002952515,0.0000183092,0.0002181641],"genre_scores_gemma":[0.3366555,0.6587874,0.001632941,0.001159798,0.0003083372,0.0004120186,0.0005725999,0.00002647756,0.0004450355],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01464077,"threshold_uncertainty_score":0.0301739,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1263964775037019,"score_gpt":0.4202591645056042,"score_spread":0.2938626870019022,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}