{"id":"W3200255374","doi":"10.1002/eji.202149318","title":"Helios is a marker, not a driver, of human Treg stability","year":2021,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Biology; Immune system; Immunology; Effector; Transcription factor; Immune tolerance; Population; Inflammation; Cancer research; Genetics; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001202833,0.0003216731,0.0009419838,0.0002838587,0.0002144072,0.0000146485,0.000784437,0.0001877351,0.006701285],"category_scores_gemma":[0.0003685251,0.0002851372,0.0005011269,0.0002877606,0.0009616876,0.0001352653,0.0004137908,0.001071825,0.0005058044],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006901244,"about_ca_system_score_gemma":0.0002866013,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002013797,"about_ca_topic_score_gemma":0.000009588886,"domain_scores_codex":[0.9945673,0.002955199,0.00147426,0.0003728189,0.00008100069,0.0005493838],"domain_scores_gemma":[0.9971357,0.0002455372,0.001133658,0.0007245007,0.0007118394,0.00004877545],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006739394,0.0006546991,0.001262746,0.00002873056,0.001109402,0.0004703963,0.001341644,8.218657e-7,0.9814858,0.0002509712,0.003689981,0.009030874],"study_design_scores_gemma":[0.004731838,0.001549378,0.01251596,0.00009278578,0.0001492165,0.002472834,0.001025605,5.345198e-7,0.9107563,0.0001151972,0.06632838,0.0002619554],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9740766,0.01664391,0.000130428,0.0009192894,0.001796681,0.00009691543,0.00004048856,0.00003116656,0.006264544],"genre_scores_gemma":[0.9943394,0.001003957,0.0003434625,0.0004274374,0.0000715779,0.000001113213,0.00002724588,0.00004380609,0.003742022],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07072949,"threshold_uncertainty_score":0.9999601,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02020040783961223,"score_gpt":0.2296826017497536,"score_spread":0.2094821939101414,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}