{"id":"W3200255374","doi":"10.1002/eji.202149318","title":"Helios is a marker, not a driver, of human Treg stability","year":2021,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Biology; Immune system; Immunology; Effector; Transcription factor; Immune tolerance; Population; Inflammation; Cancer research; Genetics; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003717565,0.0001709883,0.0001786404,0.0002727224,0.0001042116,0.000534971,0.0001146218,0.0001812251,0.001351459],"category_scores_gemma":[0.0002928251,0.0001202782,0.0001227259,0.0001587182,0.0002606547,0.0002673999,0.0002120925,0.0004436809,0.0002813181],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001648619,"about_ca_system_score_gemma":0.0001383538,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002664959,"about_ca_topic_score_gemma":0.0002901097,"domain_scores_codex":[0.9997231,0.00005895104,0.00002761028,0.00007150839,0.0000731812,0.00004559508],"domain_scores_gemma":[0.9997323,0.00007723755,0.0000890989,0.00004200979,0.00003312398,0.00002618067],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005817641,0.000006053501,0.001030608,0.00001390406,0.000004680822,0.00002791098,0.0000144051,0.00005854346,0.9973655,0.00008903959,0.00002763244,0.001303539],"study_design_scores_gemma":[0.000004573749,0.0001189592,0.00629974,0.000007059459,0.0000207795,0.0005391687,0.0000437156,0.0006978489,0.989978,0.0001164396,0.00216862,0.00000517825],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9829291,0.001406913,0.01319808,0.00007983683,0.00002829529,0.00002162716,0.000402757,0.0001977958,0.00173556],"genre_scores_gemma":[0.9964044,0.0002753924,0.002197578,0.00002934906,0.000008558016,0.00001243476,0.0002452121,0.0000247027,0.000802316],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001351459,"threshold_uncertainty_score":0.004521012,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02020040783961223,"score_gpt":0.2296826017497536,"score_spread":0.2094821939101414,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}