{"id":"W3200282004","doi":"10.1101/2021.09.17.460810","title":"Educational Attainment Polygenic Scores, Socioeconomic Factors, and Cortical Structure in Children and Adolescents","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"National Institute of Mental Health","keywords":"Neurocognitive; Socioeconomic status; Developmental psychology; Psychology; Educational attainment; Confounding; Working memory; Superior temporal gyrus; Parahippocampal gyrus; Neuropsychology; Functional magnetic resonance imaging; Cognition; Academic achievement; Clinical psychology; Medicine; Temporal lobe; Neuroscience; Population; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004444193,0.0003758887,0.0002506567,0.0009517328,0.0003342009,0.0006160039,0.0002299272,0.0003080827,0.001587222],"category_scores_gemma":[0.001438454,0.0001776731,0.0003112339,0.0008938454,0.000362414,0.00029168,0.0005019708,0.000347576,0.0001136062],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002551998,"about_ca_system_score_gemma":0.0002534152,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01362141,"about_ca_topic_score_gemma":0.01222953,"domain_scores_codex":[0.9997784,0.00004591037,0.00001960874,0.0000677924,0.00004293886,0.0000453191],"domain_scores_gemma":[0.9993069,0.0001468711,0.0003090547,0.00004562924,0.00006838253,0.0001232333],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0000248264,0.000009757231,0.9985806,0.000005146213,0.00004677035,0.000102191,0.00006925202,0.00004729739,0.0001766701,0.00003431481,0.00004370828,0.0008593991],"study_design_scores_gemma":[5.73628e-7,0.000007422501,0.9997538,0.000002109415,0.000007794732,0.00007025289,0.00004565787,0.00004466993,0.00002415169,0.00001861532,0.00002436441,6.06339e-7],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993296,0.0001584456,0.00005018464,0.00002432897,0.000001569417,0.000002374723,0.0002434342,0.000002317639,0.0001877445],"genre_scores_gemma":[0.9996203,0.00007688857,0.00005427341,0.000005953708,0.000002174206,0.000003467889,0.0001865631,0.000001227004,0.00004910718],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01362141,"threshold_uncertainty_score":0.02708429,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004496971193105615,"score_gpt":0.1997886599520602,"score_spread":0.1952916887589546,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}