{"id":"W3200458999","doi":"10.1016/j.kint.2021.08.024","title":"Proteinuric chronic kidney disease is associated with altered red blood cell lifespan, deformability and metabolism","year":2021,"lang":"en","type":"article","venue":"Kidney International","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ontario Tech University","funders":"Government of Canada; Deutsche Forschungsgemeinschaft; Canadian Blood Services; Australian Government","keywords":"Kidney disease; Anemia; Erythropoietin; Internal medicine; Endocrinology; Kidney; Erythropoiesis; Medicine; Red blood cell; Phosphatidylserine; Immunology; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001127395,0.0001839545,0.0002771849,0.00008098868,0.00007764695,0.00003040437,0.00008307664,0.00009731312,0.003407733],"category_scores_gemma":[0.001020811,0.0001503216,0.00009994817,0.0001723321,0.00009632214,0.000124223,0.00007157667,0.000246274,0.00003692689],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001206844,"about_ca_system_score_gemma":0.00132471,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000153183,"about_ca_topic_score_gemma":0.000005862106,"domain_scores_codex":[0.9986582,0.00008981997,0.0002615361,0.0004196745,0.0003450953,0.0002256204],"domain_scores_gemma":[0.9983723,0.00003711861,0.0001284496,0.0002791703,0.0004035863,0.0007793366],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.005173241,0.007274029,0.1995182,0.001377288,0.00522018,0.001366256,0.001781009,0.00002460219,0.3772729,0.001385067,0.3969397,0.002667472],"study_design_scores_gemma":[0.02802512,0.0007655882,0.4542002,0.0007373919,0.001553398,0.0003898273,0.00009168861,0.003069771,0.06870339,0.0008167518,0.4408583,0.0007886106],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9447818,0.0006713035,0.0001732372,0.0437551,0.001404091,0.0006918374,0.000778148,0.0001696755,0.007574738],"genre_scores_gemma":[0.9624635,0.0001657634,0.0007114019,0.01964089,0.0008330427,0.00009458224,0.001826337,0.00003355495,0.01423092],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3085695,"threshold_uncertainty_score":0.9975033,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01065267522390486,"score_gpt":0.2383708183633406,"score_spread":0.2277181431394357,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}