{"id":"W3200587016","doi":"10.26508/lsa.202101081","title":"Elevated glycolysis imparts functional ability to CD8<sup>+</sup> T cells in HIV infection","year":2021,"lang":"en","type":"article","venue":"Life Science Alliance","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; Maple Leaf Medical Clinic; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; University of Toronto","funders":"Scheme for Promotion of Academic and Research Collaboration; Canadian Institutes of Health Research; Hospital for Sick Children; Ontario HIV Treatment Network","keywords":"Glycolysis; Human immunodeficiency virus (HIV); CD8; Virology; Biology; Immunology; Chemistry; Metabolism; Biochemistry; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0005545893,0.0001332601,0.0001894793,0.0001185761,0.0002985819,0.00005113578,0.000195014,0.00008732517,0.001865997],"category_scores_gemma":[0.0004821994,0.0001208416,0.00006046979,0.001615133,0.0003942514,0.0002632929,0.0001296517,0.0002210557,0.007456913],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000231521,"about_ca_system_score_gemma":0.0007302765,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001867747,"about_ca_topic_score_gemma":0.0001897781,"domain_scores_codex":[0.9982048,0.000153078,0.0002392958,0.0006331494,0.0001461255,0.0006235763],"domain_scores_gemma":[0.9991208,0.0001041615,0.00003844196,0.0003876101,0.0002167331,0.0001321994],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001581613,0.0004784158,0.1698232,0.00001447963,0.0000348826,0.00002950475,0.0003379058,0.005063689,0.8153508,0.0001481096,0.006751292,0.001809588],"study_design_scores_gemma":[0.001554358,0.0002096735,0.4937348,0.00004226346,0.00001325447,0.00002333208,0.0001765895,0.0003018309,0.4544488,0.0001092732,0.04910919,0.000276624],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968643,0.000269599,0.0002317812,0.00124166,0.0002799537,0.0002477666,0.00004242491,0.00004178491,0.000780776],"genre_scores_gemma":[0.995793,0.00006800884,0.0002226991,0.0004021517,0.00002715822,0.00008124816,0.00006383549,0.000005185627,0.003336738],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.360902,"threshold_uncertainty_score":0.9990464,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02102279176408993,"score_gpt":0.2769622990412384,"score_spread":0.2559395072771485,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}