{"id":"W3200599534","doi":"10.3390/v13091829","title":"The Innate Immune DNA Sensing cGAS-STING Signaling Pathway Mediates Anti-PRRSV Function","year":2021,"lang":"en","type":"article","venue":"Viruses","topic":"Animal Virus Infections Studies","field":"Agricultural and Biological Sciences","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Priority Academic Program Development of Jiangsu Higher Education Institutions; Yangzhou University; Government of Jiangsu Province; National Natural Science Foundation of China","keywords":"Innate immune system; Sting; Porcine reproductive and respiratory syndrome virus; Biology; Gene knockdown; Virology; RIG-I; Immunity; Immune system; Virus; DNA virus; Immunology; Gene; Genetics; Genome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001584092,0.0003641762,0.0002123011,0.0001485895,0.0001318079,0.0002335641,0.00009736159,0.0002662209,0.001050353],"category_scores_gemma":[0.00007837142,0.00007337153,0.0003752896,0.00006069398,0.000219063,0.0002463921,0.0001664784,0.0003842944,0.0002574152],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001927052,"about_ca_system_score_gemma":0.0001791484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002887779,"about_ca_topic_score_gemma":0.0003563044,"domain_scores_codex":[0.9998621,0.00003440347,0.0000116605,0.00002497122,0.00002609171,0.00004070529],"domain_scores_gemma":[0.9999509,0.000006584781,0.00001502151,0.000006219357,0.000006450255,0.00001482329],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007120046,0.000009884125,0.0002380019,0.00003462292,0.00000250622,0.00003940674,0.000008687924,0.00002260239,0.9989415,0.00005217694,0.00001418219,0.0005651996],"study_design_scores_gemma":[0.0000189347,0.0005337726,0.01387218,0.00001464433,0.00001856554,0.0005142678,0.00006704974,0.001222333,0.9812075,0.00008006563,0.002445574,0.000005014459],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933722,0.002705202,0.002020172,0.0001072918,0.00002899514,0.00002172672,0.0002345738,0.00005068637,0.001459159],"genre_scores_gemma":[0.9964499,0.0007565539,0.001253071,0.00004127864,0.000009437251,0.00001479518,0.0002897348,0.000004120605,0.001181117],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001050353,"threshold_uncertainty_score":0.003513753,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03933260852978349,"score_gpt":0.2328874987997236,"score_spread":0.1935548902699401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}