{"id":"W3200612659","doi":"10.3390/biom11091382","title":"Mechanistic Target of Rapamycin Complex 1 Signaling Links Hypoxia to Increased IGFBP-1 Phosphorylation in Primary Human Decidualized Endometrial Stromal Cells","year":2021,"lang":"en","type":"article","venue":"Biomolecules","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children’s Health Research Institute; Carleton University; Western University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institutes of Health; Thomas Jefferson University","keywords":"Stromal cell; Phosphorylation; Cancer research; Hypoxia (environmental); Cell biology; Chemistry; Biology; Oxygen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004124899,0.0002866673,0.0007637891,0.0006114792,0.00007755855,0.00003196484,0.0001534769,0.0002755583,0.000327032],"category_scores_gemma":[0.0004654289,0.0002908967,0.000203549,0.001181531,0.00007846022,0.00006927223,0.0001098254,0.0002704952,0.00002570237],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001495654,"about_ca_system_score_gemma":0.0002826043,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003287059,"about_ca_topic_score_gemma":0.00001902153,"domain_scores_codex":[0.9974779,0.0002008687,0.0008711632,0.0004813221,0.0005649239,0.0004037588],"domain_scores_gemma":[0.9986796,0.0002324858,0.0002065359,0.0003625884,0.0002484324,0.0002703518],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007764066,0.0004140091,0.003356787,0.0001115991,0.0000792357,0.0001894719,0.000197386,0.000008931616,0.9936946,0.0004306209,0.0003042388,0.0004367059],"study_design_scores_gemma":[0.006210956,0.0006458759,0.05781444,0.0001336217,0.000113395,0.00001338932,0.000175118,0.00009373527,0.933783,0.0003053699,0.0004428651,0.0002682667],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926056,0.0004909041,0.004916224,0.0001114572,0.000178612,0.0006106817,0.0001154626,0.00005720768,0.0009137974],"genre_scores_gemma":[0.9781305,0.00001787341,0.02039235,0.0004732665,0.0001362669,0.00002235313,0.0007349202,0.00004602574,0.00004651246],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05991164,"threshold_uncertainty_score":0.9999543,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02764087015465063,"score_gpt":0.2744019727587452,"score_spread":0.2467611026040946,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}