{"id":"W3200620481","doi":"10.1016/j.ebiom.2021.103594","title":"Kissing genetic MS risk loci to life","year":2021,"lang":"en","type":"article","venue":"EBioMedicine","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Roman, Marga und Mareille Sobek Stiftung; Innosuisse - Schweizerische Agentur für Innovationsförderung; Universität Zürich; Swiss Vaccine Research Institute; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Mononucleosis; Immunology; Multiple sclerosis; Disease; Human leukocyte antigen; Major histocompatibility complex; Epstein–Barr virus; Immune system; Medicine; Genetic predisposition; Biology; Virus; Antigen; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001734703,0.0002001734,0.0003852411,0.0001518056,0.0002263693,0.000009616929,0.000194982,0.0002560081,0.004622825],"category_scores_gemma":[0.000287804,0.000166719,0.00007824045,0.0003960069,0.0002781731,0.00002629644,0.0001647253,0.0003668712,0.004128741],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003410553,"about_ca_system_score_gemma":0.0001325493,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000230732,"about_ca_topic_score_gemma":0.00003138593,"domain_scores_codex":[0.9984829,0.0002000271,0.0003550526,0.0004201915,0.00004508497,0.0004967333],"domain_scores_gemma":[0.9991462,0.0001122891,0.0000939678,0.0004655393,0.00009821549,0.00008384329],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005281432,0.0001163175,0.002135094,0.00001234511,0.0001641584,0.0000852572,0.0004482918,0.000002687814,0.9350591,0.00006063288,0.04246278,0.01940058],"study_design_scores_gemma":[0.001929587,0.0003548197,0.01358225,0.00004348137,0.0001020537,0.0002761715,0.0004007242,0.000002888667,0.2966944,0.0001114213,0.6862766,0.0002255903],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9613211,0.02502565,0.002194714,0.00503094,0.002582514,0.0001634315,0.00002525797,0.0001391074,0.003517323],"genre_scores_gemma":[0.9788953,0.000379174,0.0008402176,0.002666982,0.0002771011,0.00001147765,0.0001670143,0.00002574976,0.01673698],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6438138,"threshold_uncertainty_score":0.9966466,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01048732610824735,"score_gpt":0.2338373408974533,"score_spread":0.223350014789206,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}