{"id":"W3200704332","doi":"10.1139/cjc-2021-0030","title":"Lactose-conjugated porphyrin: synthesis and photobiological evaluation as potential agents for photodynamic therapy","year":2021,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Nanoplatforms for cancer theranostics","field":"Engineering","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Porphyrin; Photodynamic therapy; Chemistry; Conjugated system; Combinatorial chemistry; Cytotoxicity; Lactose; Selectivity; Conjugate; Solubility; Photochemistry; In vitro; Organic chemistry; Biochemistry; Polymer; Catalysis","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001407323,0.0002138197,0.000188025,0.0001486674,0.0001121882,0.0001696079,0.0001884723,0.0002333451,0.0006912651],"category_scores_gemma":[0.0001267386,0.00008973451,0.0001152325,0.0002050925,0.0001330475,0.0001982933,0.0001613294,0.0002425027,0.0001755995],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004350861,"about_ca_system_score_gemma":0.0001953736,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001025601,"about_ca_topic_score_gemma":0.00110346,"domain_scores_codex":[0.9999554,0.000007910669,0.000003299432,0.000008667201,0.00001308731,0.00001149795],"domain_scores_gemma":[0.9999694,0.000004827174,0.000008617934,0.000002955149,0.000005617758,0.000008685392],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005666375,0.00003819179,0.00005426688,0.00008035567,0.000004265877,0.00006314724,0.00001709708,0.0003483269,0.9942941,0.0001239324,0.00004783754,0.004871737],"study_design_scores_gemma":[0.00001436743,0.0004217059,0.0007215703,0.000004908529,0.00001318581,0.0001130302,0.00001061615,0.001069178,0.9943632,0.00003681762,0.003224021,0.000007435898],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9760995,0.009306636,0.01137092,0.0001724778,0.00002373062,0.0001893712,0.0003085385,0.0001206258,0.002408182],"genre_scores_gemma":[0.9850661,0.003586412,0.008723621,0.00005081901,0.000007230939,0.00007043534,0.0002038165,0.00002230321,0.002269237],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001025601,"threshold_uncertainty_score":0.003156781,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01484691634761154,"score_gpt":0.2275659356482896,"score_spread":0.212719019300678,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}